Nrf2 participates in mechanisms for reducing the toxicity and enhancing the antitumour effect of Radix Tripterygium wilfordii to S180-bearing mice by herbal-processing technology

Context: Radix Tripterygium wilfordii Hook. f. (Celastraceae) (LGT) has outstanding curative efficacy; however, side effects include high toxicity, particularly hepatotoxicity and nephrotoxicity. Objective: To investigate detoxification mechanisms of LGT through processing separately with each of th...

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Bibliographic Details
Main Authors: Jun-Ming Wang, Jin-Yang Li, Hong Cai, Rong-Xing Chen, Yue-Yue Zhang, Lu-Lu Zhang, Ying Cui, Yong-Xian Cheng
Format: article
Language:EN
Published: Taylor & Francis Group 2019
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Online Access:https://doaj.org/article/59684b64a4fe4e34963c854d31ac364a
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