Evolution of a General RNA-Cleaving FANA Enzyme
Artificial genetic polymers (XNAs) have been explored for their nuclease activity, but XNAzymes have proven challenging to discover by in vitro selection. Here, the authors generate an efficient RNA-cleaving 2’-fluoroarabino nucleic acid enzyme (FANAzyme) by in vitro evolution using natural DNA poly...
Guardado en:
Autores principales: | Yajun Wang, Arlene K. Ngor, Ali Nikoomanzar, John C. Chaput |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/596b420be50f478c8b1343b5a6191768 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Crystal structure of an RNA-cleaving DNAzyme
por: Hehua Liu, et al.
Publicado: (2017) -
A YoeB toxin cleaves both RNA and DNA
por: Julia McGillick, et al.
Publicado: (2021) -
C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes
por: Takahiro Mori, et al.
Publicado: (2021) -
Structural basis for TNA synthesis by an engineered TNA polymerase
por: Nicholas Chim, et al.
Publicado: (2017) -
Clean, cleaved surfaces of the photovoltaic perovskite
por: Márton Kollár, et al.
Publicado: (2017)