Protein tyrosine phosphatase Shp2 deficiency in podocytes attenuates lipopolysaccharide-induced proteinuria
Abstract Podocytes are specialized epithelial cells that play a significant role in maintaining the integrity of the glomerular filtration barrier and preventing urinary protein leakage. We investigated the contribution of protein tyrosine phosphatase Shp2 to lipopolysaccharide (LPS)-induced renal i...
Saved in:
Main Authors: | Ming-Fo Hsu, Ahmed Bettaieb, Yoshihiro Ito, James Graham, Peter J. Havel, Fawaz G. Haj |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/596de7c5fb144f74bc697024e074dc19 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling
by: Min Liu, et al.
Published: (2017) -
Myo1e impairment results in actin reorganization, podocyte dysfunction, and proteinuria in zebrafish and cultured podocytes.
by: Jianhua Mao, et al.
Published: (2013) -
The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis
by: Ariella Zehender, et al.
Published: (2018) -
Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis
by: Wenjie Guo, et al.
Published: (2017) -
Retraction Note: Transplantation of Mouse Induced Pluripotent Stem Cell-Derived Podocytes in a Mouse Model of Membranous Nephropathy Attenuates Proteinuria
by: Amin Ahmadi, et al.
Published: (2021)