Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters

The Drosophila dopamine transporter (dDAT) is a catecholamine neurotransmitter transporter that resembles the human norepinephrine transporter (hNET). Here the authors report X-ray structures of the dDAT in substrate-free form, norepinephrine-bound form and dDAT bound to commonly prescribed chronic...

Full description

Saved in:
Bibliographic Details
Main Authors: Shabareesh Pidathala, Aditya Kumar Mallela, Deepthi Joseph, Aravind Penmatsa
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Q
Online Access:https://doaj.org/article/596e7b01288047a2ae7f7113ab49a0d6
Tags: Add Tag
No Tags, Be the first to tag this record!