The Itch-Scratch Cycle: A Review of the Mechanisms

Background: Despite being one of the most common presenting dermatological symptoms, itching continues to perplex health care professionals because it is notoriously difficult to control. Objective: This review gathers evidence to answer the 2-part question, “Why do we itch and scratch?” by expl...

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Autor principal:	Giulia Rinaldi
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2019
Materias:	itch prurigo scratch pruritus Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/5977c6b9bee54e198fb8294bd4730a79
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spelling	oai:doaj.org-article:5977c6b9bee54e198fb8294bd4730a792021-11-17T08:29:31ZThe Itch-Scratch Cycle: A Review of the Mechanisms10.5826/dpc.0902a032160-9381https://doaj.org/article/5977c6b9bee54e198fb8294bd4730a792019-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/648https://doaj.org/toc/2160-9381 Background: Despite being one of the most common presenting dermatological symptoms, itching continues to perplex health care professionals because it is notoriously difficult to control. Objective: This review gathers evidence to answer the 2-part question, “Why do we itch and scratch?” by exploring the history of itchy disease, the neurobiology of itch, and the 4 different clinical origins of itch: pruritogenic, neurological, neuropathic, and psychological. Results: The automated scratching reflex and its biological and psychological reasons for existence are complicated and poorly understood. Currently, there are a myriad of treatments available for individuals suffering from this condition; however, many remain symptomatic. Conclusions: The itch-scratch cycle is a complex pain-like sensation with a reflex-like response. In the future, continued exploration into the mechanisms behind itch and scratch may open the doors for new therapeutic interventions. Giulia RinaldiMattioli1885articleitchprurigoscratchpruritusDermatologyRL1-803ENDermatology Practical & Conceptual, Vol 9, Iss 2 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	itch prurigo scratch pruritus Dermatology RL1-803
spellingShingle	itch prurigo scratch pruritus Dermatology RL1-803 Giulia Rinaldi The Itch-Scratch Cycle: A Review of the Mechanisms
description	Background: Despite being one of the most common presenting dermatological symptoms, itching continues to perplex health care professionals because it is notoriously difficult to control. Objective: This review gathers evidence to answer the 2-part question, “Why do we itch and scratch?” by exploring the history of itchy disease, the neurobiology of itch, and the 4 different clinical origins of itch: pruritogenic, neurological, neuropathic, and psychological. Results: The automated scratching reflex and its biological and psychological reasons for existence are complicated and poorly understood. Currently, there are a myriad of treatments available for individuals suffering from this condition; however, many remain symptomatic. Conclusions: The itch-scratch cycle is a complex pain-like sensation with a reflex-like response. In the future, continued exploration into the mechanisms behind itch and scratch may open the doors for new therapeutic interventions.
format	article
author	Giulia Rinaldi
author_facet	Giulia Rinaldi
author_sort	Giulia Rinaldi
title	The Itch-Scratch Cycle: A Review of the Mechanisms
title_short	The Itch-Scratch Cycle: A Review of the Mechanisms
title_full	The Itch-Scratch Cycle: A Review of the Mechanisms
title_fullStr	The Itch-Scratch Cycle: A Review of the Mechanisms
title_full_unstemmed	The Itch-Scratch Cycle: A Review of the Mechanisms
title_sort	itch-scratch cycle: a review of the mechanisms
publisher	Mattioli1885
publishDate	2019
url	https://doaj.org/article/5977c6b9bee54e198fb8294bd4730a79
work_keys_str_mv	AT giuliarinaldi theitchscratchcycleareviewofthemechanisms AT giuliarinaldi itchscratchcycleareviewofthemechanisms
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The Itch-Scratch Cycle: A Review of the Mechanisms

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