Gender differences in health-related quality of life measured by the Sarcoidosis Health Questionnaire

Abstract Sarcoidosis is granulomatous disease, which complex etiology is yet to be fully discovered. In the majority of cases its course is self-limiting. However it can have different clinical manifestations and can be debilitating condition with great impact on health-related quality of life (HRQL...

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Autores principales:	Łukasz Gwadera, Adam J. Białas, Witold Górski, Mikołaj A. Iwański, Joanna Miłkowska-Dymanowska, Paweł Górski, Wojciech J. Piotrowski
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/597f4bb8b2834a2b9b020b7ad2aa142a
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spelling	oai:doaj.org-article:597f4bb8b2834a2b9b020b7ad2aa142a2021-12-02T15:43:17ZGender differences in health-related quality of life measured by the Sarcoidosis Health Questionnaire10.1038/s41598-021-89383-12045-2322https://doaj.org/article/597f4bb8b2834a2b9b020b7ad2aa142a2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-89383-1https://doaj.org/toc/2045-2322Abstract Sarcoidosis is granulomatous disease, which complex etiology is yet to be fully discovered. In the majority of cases its course is self-limiting. However it can have different clinical manifestations and can be debilitating condition with great impact on health-related quality of life (HRQL). The aim of our study was to assess if there are any differences in HRQL dependent to gender. We examined a group of 33 males and 42 females (with no differences in mean age, disease activity, TLCO, FEV1, FVC, FEV1/FVC) with a use of Sarcoidosis Health Questionnaire. We revealed lower total and daily functioning score in female group. Further analyses stratified by sex and activity of the disease presented many significant differences between the groups, revealing important issues for the discussion about gender specific differences in the HRQL of patients with sarcoidosis. In spite of clinical presentation may be similar, expectations and main concerns of sarcoidosis patient can vary between females and males. Therefore, it appears that in terms of education and symptomatic treatment accents should be put differently depending on the gender of the patient. Our results may also point to a need for more gender-oriented patient-physician communication which could enable better understanding, potentially improve adherence to therapy and decrease the risk of possible complications.Łukasz GwaderaAdam J. BiałasWitold GórskiMikołaj A. IwańskiJoanna Miłkowska-DymanowskaPaweł GórskiWojciech J. PiotrowskiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Łukasz Gwadera Adam J. Białas Witold Górski Mikołaj A. Iwański Joanna Miłkowska-Dymanowska Paweł Górski Wojciech J. Piotrowski Gender differences in health-related quality of life measured by the Sarcoidosis Health Questionnaire
description	Abstract Sarcoidosis is granulomatous disease, which complex etiology is yet to be fully discovered. In the majority of cases its course is self-limiting. However it can have different clinical manifestations and can be debilitating condition with great impact on health-related quality of life (HRQL). The aim of our study was to assess if there are any differences in HRQL dependent to gender. We examined a group of 33 males and 42 females (with no differences in mean age, disease activity, TLCO, FEV1, FVC, FEV1/FVC) with a use of Sarcoidosis Health Questionnaire. We revealed lower total and daily functioning score in female group. Further analyses stratified by sex and activity of the disease presented many significant differences between the groups, revealing important issues for the discussion about gender specific differences in the HRQL of patients with sarcoidosis. In spite of clinical presentation may be similar, expectations and main concerns of sarcoidosis patient can vary between females and males. Therefore, it appears that in terms of education and symptomatic treatment accents should be put differently depending on the gender of the patient. Our results may also point to a need for more gender-oriented patient-physician communication which could enable better understanding, potentially improve adherence to therapy and decrease the risk of possible complications.
format	article
author	Łukasz Gwadera Adam J. Białas Witold Górski Mikołaj A. Iwański Joanna Miłkowska-Dymanowska Paweł Górski Wojciech J. Piotrowski
author_facet	Łukasz Gwadera Adam J. Białas Witold Górski Mikołaj A. Iwański Joanna Miłkowska-Dymanowska Paweł Górski Wojciech J. Piotrowski
author_sort	Łukasz Gwadera
title	Gender differences in health-related quality of life measured by the Sarcoidosis Health Questionnaire
title_short	Gender differences in health-related quality of life measured by the Sarcoidosis Health Questionnaire
title_full	Gender differences in health-related quality of life measured by the Sarcoidosis Health Questionnaire
title_fullStr	Gender differences in health-related quality of life measured by the Sarcoidosis Health Questionnaire
title_full_unstemmed	Gender differences in health-related quality of life measured by the Sarcoidosis Health Questionnaire
title_sort	gender differences in health-related quality of life measured by the sarcoidosis health questionnaire
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/597f4bb8b2834a2b9b020b7ad2aa142a
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Gender differences in health-related quality of life measured by the Sarcoidosis Health Questionnaire

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