Patient and haemodynamic factors affecting intraoperative graft flow during coronary artery bypass grafting: an observational pilot study

Abstract Transit-time flow measurement (TTFM) is frequently used to evaluate intraoperative quality control during coronary artery bypass grafting (CABG) and has the ability to assess graft failure intraoperatively. However, perioperative factors affecting TTFM during CABG remain poorly understood....

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Autores principales:	Sang-Wook Lee, Jun-Young Jo, Wook-Jong Kim, Dae-Kee Choi, In-Cheol Choi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5982feba1cd64ef3b5ac2c4ebf1aeeb6
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spelling	oai:doaj.org-article:5982feba1cd64ef3b5ac2c4ebf1aeeb62021-12-02T16:06:39ZPatient and haemodynamic factors affecting intraoperative graft flow during coronary artery bypass grafting: an observational pilot study10.1038/s41598-020-69924-w2045-2322https://doaj.org/article/5982feba1cd64ef3b5ac2c4ebf1aeeb62020-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-69924-whttps://doaj.org/toc/2045-2322Abstract Transit-time flow measurement (TTFM) is frequently used to evaluate intraoperative quality control during coronary artery bypass grafting (CABG) and has the ability to assess graft failure intraoperatively. However, perioperative factors affecting TTFM during CABG remain poorly understood. Patients who underwent CABG at a single institution between July 2016 and May 2018 were prospectively evaluated. TTFM and blood viscosity were measured haemodynamically, while mean flow (mL/min), pulsatility index, and diastolic filling were recorded. Arterial blood gas was analysed immediately after left internal mammary artery to left descending artery anastomosis and before sternal closure. Factors associated with TTFM were assessed using multiple linear regression analysis. We evaluated 57 of the 62 patients who underwent CABG during the study period, including 49 who underwent off-pump and 8 who underwent on-pump surgeries. Blood viscosity was not significantly associated with TTFM (p > 0.05). However, TTFM was significantly associated with body mass index, systolic blood pressure, and cardiac index (p < 0.05 each). In conclusion, maintaining the SBP in the perioperative period and maintaining the CI with inotropic support or fluid resuscitation can be important in improving blood flow of graft vessels after surgery.Sang-Wook LeeJun-Young JoWook-Jong KimDae-Kee ChoiIn-Cheol ChoiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Sang-Wook Lee Jun-Young Jo Wook-Jong Kim Dae-Kee Choi In-Cheol Choi Patient and haemodynamic factors affecting intraoperative graft flow during coronary artery bypass grafting: an observational pilot study
description	Abstract Transit-time flow measurement (TTFM) is frequently used to evaluate intraoperative quality control during coronary artery bypass grafting (CABG) and has the ability to assess graft failure intraoperatively. However, perioperative factors affecting TTFM during CABG remain poorly understood. Patients who underwent CABG at a single institution between July 2016 and May 2018 were prospectively evaluated. TTFM and blood viscosity were measured haemodynamically, while mean flow (mL/min), pulsatility index, and diastolic filling were recorded. Arterial blood gas was analysed immediately after left internal mammary artery to left descending artery anastomosis and before sternal closure. Factors associated with TTFM were assessed using multiple linear regression analysis. We evaluated 57 of the 62 patients who underwent CABG during the study period, including 49 who underwent off-pump and 8 who underwent on-pump surgeries. Blood viscosity was not significantly associated with TTFM (p > 0.05). However, TTFM was significantly associated with body mass index, systolic blood pressure, and cardiac index (p < 0.05 each). In conclusion, maintaining the SBP in the perioperative period and maintaining the CI with inotropic support or fluid resuscitation can be important in improving blood flow of graft vessels after surgery.
format	article
author	Sang-Wook Lee Jun-Young Jo Wook-Jong Kim Dae-Kee Choi In-Cheol Choi
author_facet	Sang-Wook Lee Jun-Young Jo Wook-Jong Kim Dae-Kee Choi In-Cheol Choi
author_sort	Sang-Wook Lee
title	Patient and haemodynamic factors affecting intraoperative graft flow during coronary artery bypass grafting: an observational pilot study
title_short	Patient and haemodynamic factors affecting intraoperative graft flow during coronary artery bypass grafting: an observational pilot study
title_full	Patient and haemodynamic factors affecting intraoperative graft flow during coronary artery bypass grafting: an observational pilot study
title_fullStr	Patient and haemodynamic factors affecting intraoperative graft flow during coronary artery bypass grafting: an observational pilot study
title_full_unstemmed	Patient and haemodynamic factors affecting intraoperative graft flow during coronary artery bypass grafting: an observational pilot study
title_sort	patient and haemodynamic factors affecting intraoperative graft flow during coronary artery bypass grafting: an observational pilot study
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/5982feba1cd64ef3b5ac2c4ebf1aeeb6
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_version_	1718384903520780288

Patient and haemodynamic factors affecting intraoperative graft flow during coronary artery bypass grafting: an observational pilot study

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