Generation of stem cell-derived β-cells from patients with type 1 diabetes

Pancreatic β cells can be generated from pluripotent stem cells. Here, the authors show that human induced pluripotent stem cells from patients with type 1 diabetes can be differentiated into β-like cells that have no detectable differences compared with cells from non-diabetic individuals.

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Autores principales:	Jeffrey R. Millman, Chunhui Xie, Alana Van Dervort, Mads Gürtler, Felicia W. Pagliuca, Douglas A. Melton
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/598e2be6e99e4601b6f3ee9c92e2e009
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spelling	oai:doaj.org-article:598e2be6e99e4601b6f3ee9c92e2e0092021-12-02T17:31:35ZGeneration of stem cell-derived β-cells from patients with type 1 diabetes10.1038/ncomms114632041-1723https://doaj.org/article/598e2be6e99e4601b6f3ee9c92e2e0092016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11463https://doaj.org/toc/2041-1723Pancreatic β cells can be generated from pluripotent stem cells. Here, the authors show that human induced pluripotent stem cells from patients with type 1 diabetes can be differentiated into β-like cells that have no detectable differences compared with cells from non-diabetic individuals.Jeffrey R. MillmanChunhui XieAlana Van DervortMads GürtlerFelicia W. PagliucaDouglas A. MeltonNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jeffrey R. Millman Chunhui Xie Alana Van Dervort Mads Gürtler Felicia W. Pagliuca Douglas A. Melton Generation of stem cell-derived β-cells from patients with type 1 diabetes
description	Pancreatic β cells can be generated from pluripotent stem cells. Here, the authors show that human induced pluripotent stem cells from patients with type 1 diabetes can be differentiated into β-like cells that have no detectable differences compared with cells from non-diabetic individuals.
format	article
author	Jeffrey R. Millman Chunhui Xie Alana Van Dervort Mads Gürtler Felicia W. Pagliuca Douglas A. Melton
author_facet	Jeffrey R. Millman Chunhui Xie Alana Van Dervort Mads Gürtler Felicia W. Pagliuca Douglas A. Melton
author_sort	Jeffrey R. Millman
title	Generation of stem cell-derived β-cells from patients with type 1 diabetes
title_short	Generation of stem cell-derived β-cells from patients with type 1 diabetes
title_full	Generation of stem cell-derived β-cells from patients with type 1 diabetes
title_fullStr	Generation of stem cell-derived β-cells from patients with type 1 diabetes
title_full_unstemmed	Generation of stem cell-derived β-cells from patients with type 1 diabetes
title_sort	generation of stem cell-derived β-cells from patients with type 1 diabetes
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/598e2be6e99e4601b6f3ee9c92e2e009
work_keys_str_mv	AT jeffreyrmillman generationofstemcellderivedbcellsfrompatientswithtype1diabetes AT chunhuixie generationofstemcellderivedbcellsfrompatientswithtype1diabetes AT alanavandervort generationofstemcellderivedbcellsfrompatientswithtype1diabetes AT madsgurtler generationofstemcellderivedbcellsfrompatientswithtype1diabetes AT feliciawpagliuca generationofstemcellderivedbcellsfrompatientswithtype1diabetes AT douglasamelton generationofstemcellderivedbcellsfrompatientswithtype1diabetes
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Generation of stem cell-derived β-cells from patients with type 1 diabetes

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