Surgical site infections after deep brain stimulation surgery: frequency, characteristics and management in a 10-year period.

<h4>Background/aims</h4>Deep brain stimulation (DBS) implant infection is a feared complication, as it is difficult to manage and leads to increased patient morbidity. We wanted to assess the frequency and possible risk factors of DBS related infections at our centre. In the purpose of e...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Silje Bjerknes, Inger Marie Skogseid, Terje Sæhle, Espen Dietrichs, Mathias Toft
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/59918f6e55bd49efa74f5e32494d7ec7
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:59918f6e55bd49efa74f5e32494d7ec7
record_format	dspace
spelling	oai:doaj.org-article:59918f6e55bd49efa74f5e32494d7ec72021-11-25T06:04:39ZSurgical site infections after deep brain stimulation surgery: frequency, characteristics and management in a 10-year period.1932-620310.1371/journal.pone.0105288https://doaj.org/article/59918f6e55bd49efa74f5e32494d7ec72014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25122445/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background/aims</h4>Deep brain stimulation (DBS) implant infection is a feared complication, as it is difficult to manage and leads to increased patient morbidity. We wanted to assess the frequency and possible risk factors of DBS related infections at our centre. In the purpose of evaluating treatment options, we also analyzed treatment, and the clinical and microbiological characteristics of the infections.<h4>Methods</h4>Electronic medical records of all patients undergoing DBS surgery at our centre, from 2001 through 2010, were retrospectively reviewed.<h4>Results</h4>Of the 588 procedures performed 33 (5.6%) led to an infection. Some patients underwent several procedures, thus 32 out of totally 368 patients (8.7%), and 19 out of 285 patients (6.7%) who received primary lead implantation, developed an infection. Most infections (52%) developed within the first month and 79% within three months. In the majority of the infections (79%) hardware removal was performed. Staphylococcus aureus infections were the most frequent (36%), and more likely to have earlier onset, pus formation, a more aggressive development and lead to hardware removal. No risk factors were identified.<h4>Conclusions</h4>Our results indicate that infections with more severe symptoms and growth of staphylococcus aureus should be treated with local hardware removal and antibiotic therapy. In other infections, an initial trial of antibiotic treatment could be considered. New knowledge about the microbiology of DBS related infections may lead to more effective antimicrobial treatment.Silje BjerknesInger Marie SkogseidTerje SæhleEspen DietrichsMathias ToftPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 8, p e105288 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Silje Bjerknes Inger Marie Skogseid Terje Sæhle Espen Dietrichs Mathias Toft Surgical site infections after deep brain stimulation surgery: frequency, characteristics and management in a 10-year period.
description	<h4>Background/aims</h4>Deep brain stimulation (DBS) implant infection is a feared complication, as it is difficult to manage and leads to increased patient morbidity. We wanted to assess the frequency and possible risk factors of DBS related infections at our centre. In the purpose of evaluating treatment options, we also analyzed treatment, and the clinical and microbiological characteristics of the infections.<h4>Methods</h4>Electronic medical records of all patients undergoing DBS surgery at our centre, from 2001 through 2010, were retrospectively reviewed.<h4>Results</h4>Of the 588 procedures performed 33 (5.6%) led to an infection. Some patients underwent several procedures, thus 32 out of totally 368 patients (8.7%), and 19 out of 285 patients (6.7%) who received primary lead implantation, developed an infection. Most infections (52%) developed within the first month and 79% within three months. In the majority of the infections (79%) hardware removal was performed. Staphylococcus aureus infections were the most frequent (36%), and more likely to have earlier onset, pus formation, a more aggressive development and lead to hardware removal. No risk factors were identified.<h4>Conclusions</h4>Our results indicate that infections with more severe symptoms and growth of staphylococcus aureus should be treated with local hardware removal and antibiotic therapy. In other infections, an initial trial of antibiotic treatment could be considered. New knowledge about the microbiology of DBS related infections may lead to more effective antimicrobial treatment.
format	article
author	Silje Bjerknes Inger Marie Skogseid Terje Sæhle Espen Dietrichs Mathias Toft
author_facet	Silje Bjerknes Inger Marie Skogseid Terje Sæhle Espen Dietrichs Mathias Toft
author_sort	Silje Bjerknes
title	Surgical site infections after deep brain stimulation surgery: frequency, characteristics and management in a 10-year period.
title_short	Surgical site infections after deep brain stimulation surgery: frequency, characteristics and management in a 10-year period.
title_full	Surgical site infections after deep brain stimulation surgery: frequency, characteristics and management in a 10-year period.
title_fullStr	Surgical site infections after deep brain stimulation surgery: frequency, characteristics and management in a 10-year period.
title_full_unstemmed	Surgical site infections after deep brain stimulation surgery: frequency, characteristics and management in a 10-year period.
title_sort	surgical site infections after deep brain stimulation surgery: frequency, characteristics and management in a 10-year period.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/59918f6e55bd49efa74f5e32494d7ec7
work_keys_str_mv	AT siljebjerknes surgicalsiteinfectionsafterdeepbrainstimulationsurgeryfrequencycharacteristicsandmanagementina10yearperiod AT ingermarieskogseid surgicalsiteinfectionsafterdeepbrainstimulationsurgeryfrequencycharacteristicsandmanagementina10yearperiod AT terjesæhle surgicalsiteinfectionsafterdeepbrainstimulationsurgeryfrequencycharacteristicsandmanagementina10yearperiod AT espendietrichs surgicalsiteinfectionsafterdeepbrainstimulationsurgeryfrequencycharacteristicsandmanagementina10yearperiod AT mathiastoft surgicalsiteinfectionsafterdeepbrainstimulationsurgeryfrequencycharacteristicsandmanagementina10yearperiod
_version_	1718414224024141824

Surgical site infections after deep brain stimulation surgery: frequency, characteristics and management in a 10-year period.

Ejemplares similares