Early stability and late random tumor progression of a HER2-positive primary breast cancer patient-derived xenograft

Early stability and late random tumor progression of a HER2-positive primary breast cancer patient-derived xenograft

Abstract We established patient-derived xenografts (PDX) from human primary breast cancers and studied whether stability or progressive events occurred during long-term in vivo passages (up to 4 years) in severely immunodeficient mice. While most PDX showed stable biomarker expression and growth phe...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Lorena Landuzzi, Arianna Palladini, Claudio Ceccarelli, Sofia Asioli, Giordano Nicoletti, Veronica Giusti, Francesca Ruzzi, Marianna L. Ianzano, Laura Scalambra, Roberta Laranga, Tania Balboni, Maddalena Arigoni, Martina Olivero, Raffaele A. Calogero, Carla De Giovanni, Massimiliano Dall’Ora, Enrico Di Oto, Donatella Santini, Maria Pia Foschini, Maria Cristina Cucchi, Simone Zanotti, Mario Taffurelli, Patrizia Nanni, Pier-Luigi Lollini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/59a0895a37d34757859e7e9b853a7ad6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares