Circulating primitive erythroblasts establish a functional, protein 4.1R-dependent cytoskeletal network prior to enucleating

Circulating primitive erythroblasts establish a functional, protein 4.1R-dependent cytoskeletal network prior to enucleating

Abstract Hematopoietic ontogeny is characterized by distinct primitive and definitive erythroid lineages. Definitive erythroblasts mature and enucleate extravascularly and form a unique membrane skeleton, composed of spectrin, 4.1R-complex, and ankyrinR-complex components, to survive the vicissitude...

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Autores principales: Yu-Shan Huang, Luis F. Delgadillo, Kathryn H. Cyr, Paul D. Kingsley, Xiuli An, Kathleen E. McGrath, Narla Mohandas, John G. Conboy, Richard E. Waugh, Jiandi Wan, James Palis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/59ae1bf1686e4ba7bff3a96a98431c78
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