Interplay between α2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory
Memory consolidation theory suggests that memory is maintained at a stable strength after formation. The authors show that memory is dynamically maintained at an intermediate level allowing a bidirectional regulation which is mediated by a balance between activated Rac1 and expressed α2-chimaerin.
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Nature Portfolio
2019
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oai:doaj.org-article:59b7addfb29a49d7a3e66465766dc4a32021-12-02T17:32:40ZInterplay between α2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory10.1038/s41467-019-13236-92041-1723https://doaj.org/article/59b7addfb29a49d7a3e66465766dc4a32019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13236-9https://doaj.org/toc/2041-1723Memory consolidation theory suggests that memory is maintained at a stable strength after formation. The authors show that memory is dynamically maintained at an intermediate level allowing a bidirectional regulation which is mediated by a balance between activated Rac1 and expressed α2-chimaerin.Li LvYunlong LiuJianxin XieYan WuJianjian ZhaoQian LiYi ZhongNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019) |
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Science Q Li Lv Yunlong Liu Jianxin Xie Yan Wu Jianjian Zhao Qian Li Yi Zhong Interplay between α2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory |
description |
Memory consolidation theory suggests that memory is maintained at a stable strength after formation. The authors show that memory is dynamically maintained at an intermediate level allowing a bidirectional regulation which is mediated by a balance between activated Rac1 and expressed α2-chimaerin. |
format |
article |
author |
Li Lv Yunlong Liu Jianxin Xie Yan Wu Jianjian Zhao Qian Li Yi Zhong |
author_facet |
Li Lv Yunlong Liu Jianxin Xie Yan Wu Jianjian Zhao Qian Li Yi Zhong |
author_sort |
Li Lv |
title |
Interplay between α2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory |
title_short |
Interplay between α2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory |
title_full |
Interplay between α2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory |
title_fullStr |
Interplay between α2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory |
title_full_unstemmed |
Interplay between α2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory |
title_sort |
interplay between α2-chimaerin and rac1 activity determines dynamic maintenance of long-term memory |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/59b7addfb29a49d7a3e66465766dc4a3 |
work_keys_str_mv |
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_version_ |
1718380248352948224 |