Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells

Dendritic cells instruct different types of T cell responses depending on the types of microbial ligands sensed. Here the authors show that dendritic cells stimulated via Dectin-1 receptor upregulate TNFSF15 and OX40L and induce T helper 9 response and efficient antitumour immunity in mouse models.

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Autores principales:	Yinghua Zhao, Xiao Chu, Jintong Chen, Ying Wang, Sujun Gao, Yuxue Jiang, Xiaoqing Zhu, Guangyun Tan, Wenjie Zhao, Huanfa Yi, Honglin Xu, Xingzhe Ma, Yong Lu, Qing Yi, Siqing Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/59baace985754d9f831df4c17c10a877
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:59baace985754d9f831df4c17c10a8772021-12-02T16:57:18ZDectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells10.1038/ncomms123682041-1723https://doaj.org/article/59baace985754d9f831df4c17c10a8772016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12368https://doaj.org/toc/2041-1723Dendritic cells instruct different types of T cell responses depending on the types of microbial ligands sensed. Here the authors show that dendritic cells stimulated via Dectin-1 receptor upregulate TNFSF15 and OX40L and induce T helper 9 response and efficient antitumour immunity in mouse models.Yinghua ZhaoXiao ChuJintong ChenYing WangSujun GaoYuxue JiangXiaoqing ZhuGuangyun TanWenjie ZhaoHuanfa YiHonglin XuXingzhe MaYong LuQing YiSiqing WangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yinghua Zhao Xiao Chu Jintong Chen Ying Wang Sujun Gao Yuxue Jiang Xiaoqing Zhu Guangyun Tan Wenjie Zhao Huanfa Yi Honglin Xu Xingzhe Ma Yong Lu Qing Yi Siqing Wang Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells
description	Dendritic cells instruct different types of T cell responses depending on the types of microbial ligands sensed. Here the authors show that dendritic cells stimulated via Dectin-1 receptor upregulate TNFSF15 and OX40L and induce T helper 9 response and efficient antitumour immunity in mouse models.
format	article
author	Yinghua Zhao Xiao Chu Jintong Chen Ying Wang Sujun Gao Yuxue Jiang Xiaoqing Zhu Guangyun Tan Wenjie Zhao Huanfa Yi Honglin Xu Xingzhe Ma Yong Lu Qing Yi Siqing Wang
author_facet	Yinghua Zhao Xiao Chu Jintong Chen Ying Wang Sujun Gao Yuxue Jiang Xiaoqing Zhu Guangyun Tan Wenjie Zhao Huanfa Yi Honglin Xu Xingzhe Ma Yong Lu Qing Yi Siqing Wang
author_sort	Yinghua Zhao
title	Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells
title_short	Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells
title_full	Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells
title_fullStr	Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells
title_full_unstemmed	Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells
title_sort	dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of th9 cells
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/59baace985754d9f831df4c17c10a877
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Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells

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