Risk factors for deep surgical site infection after posterior cervical spine surgery in adults: a multicentre observational cohort study

Abstract Surgical site infection (SSI) is a serious complication following spine surgery and is correlated with significant morbidities, poor clinical outcomes, and increased healthcare costs. Accurately identifying risk factors can help develop strategies to reduce this devastating consequence; how...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Satoshi Ogihara, Takashi Yamazaki, Michio Shiibashi, Hirotaka Chikuda, Toru Maruyama, Kota Miyoshi, Hirohiko Inanami, Yasushi Oshima, Seiichi Azuma, Naohiro Kawamura, Kiyofumi Yamakawa, Nobuhiro Hara, Jiro Morii, Rentaro Okazaki, Yujiro Takeshita, Junji Nishimoto, Sakae Tanaka, Kazuo Saita
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/59cbf2c0217747729b8dce5f7c13e408
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:59cbf2c0217747729b8dce5f7c13e408
record_format	dspace
spelling	oai:doaj.org-article:59cbf2c0217747729b8dce5f7c13e4082021-12-02T14:20:43ZRisk factors for deep surgical site infection after posterior cervical spine surgery in adults: a multicentre observational cohort study10.1038/s41598-021-87110-42045-2322https://doaj.org/article/59cbf2c0217747729b8dce5f7c13e4082021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-87110-4https://doaj.org/toc/2045-2322Abstract Surgical site infection (SSI) is a serious complication following spine surgery and is correlated with significant morbidities, poor clinical outcomes, and increased healthcare costs. Accurately identifying risk factors can help develop strategies to reduce this devastating consequence; however, few multicentre studies have investigated risk factors for SSI following posterior cervical spine surgeries. Between July 2010 and June 2015, we performed an observational cohort study on deep SSI in adult patients who underwent posterior cervical spine surgery at 10 research hospitals. Detailed patient- and procedure-specific potential risk variables were prospectively recorded using a standardised data collection chart and were reviewed retrospectively. Among the 2184 consecutive adult patients enrolled, 28 (1.3%) developed postoperative deep SSI. Multivariable regression analysis revealed 2 statistically significant independent risk factors: occipitocervical surgery (P < 0.001) and male sex (P = 0.024). Subgroup analysis demonstrated that occipitocervical surgery (P = 0.001) was the sole independent risk factor for deep SSI in patients with instrumented fusion. Occipitocervical surgery is a relatively rare procedure; therefore, our findings were based on a large cohort acquired using a multicentre study. To the best of our knowledge, this is the first study to identify occipitocervical procedure as an independent risk variable for deep SSI after spinal surgery.Satoshi OgiharaTakashi YamazakiMichio ShiibashiHirotaka ChikudaToru MaruyamaKota MiyoshiHirohiko InanamiYasushi OshimaSeiichi AzumaNaohiro KawamuraKiyofumi YamakawaNobuhiro HaraJiro MoriiRentaro OkazakiYujiro TakeshitaJunji NishimotoSakae TanakaKazuo SaitaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Satoshi Ogihara Takashi Yamazaki Michio Shiibashi Hirotaka Chikuda Toru Maruyama Kota Miyoshi Hirohiko Inanami Yasushi Oshima Seiichi Azuma Naohiro Kawamura Kiyofumi Yamakawa Nobuhiro Hara Jiro Morii Rentaro Okazaki Yujiro Takeshita Junji Nishimoto Sakae Tanaka Kazuo Saita Risk factors for deep surgical site infection after posterior cervical spine surgery in adults: a multicentre observational cohort study
description	Abstract Surgical site infection (SSI) is a serious complication following spine surgery and is correlated with significant morbidities, poor clinical outcomes, and increased healthcare costs. Accurately identifying risk factors can help develop strategies to reduce this devastating consequence; however, few multicentre studies have investigated risk factors for SSI following posterior cervical spine surgeries. Between July 2010 and June 2015, we performed an observational cohort study on deep SSI in adult patients who underwent posterior cervical spine surgery at 10 research hospitals. Detailed patient- and procedure-specific potential risk variables were prospectively recorded using a standardised data collection chart and were reviewed retrospectively. Among the 2184 consecutive adult patients enrolled, 28 (1.3%) developed postoperative deep SSI. Multivariable regression analysis revealed 2 statistically significant independent risk factors: occipitocervical surgery (P < 0.001) and male sex (P = 0.024). Subgroup analysis demonstrated that occipitocervical surgery (P = 0.001) was the sole independent risk factor for deep SSI in patients with instrumented fusion. Occipitocervical surgery is a relatively rare procedure; therefore, our findings were based on a large cohort acquired using a multicentre study. To the best of our knowledge, this is the first study to identify occipitocervical procedure as an independent risk variable for deep SSI after spinal surgery.
format	article
author	Satoshi Ogihara Takashi Yamazaki Michio Shiibashi Hirotaka Chikuda Toru Maruyama Kota Miyoshi Hirohiko Inanami Yasushi Oshima Seiichi Azuma Naohiro Kawamura Kiyofumi Yamakawa Nobuhiro Hara Jiro Morii Rentaro Okazaki Yujiro Takeshita Junji Nishimoto Sakae Tanaka Kazuo Saita
author_facet	Satoshi Ogihara Takashi Yamazaki Michio Shiibashi Hirotaka Chikuda Toru Maruyama Kota Miyoshi Hirohiko Inanami Yasushi Oshima Seiichi Azuma Naohiro Kawamura Kiyofumi Yamakawa Nobuhiro Hara Jiro Morii Rentaro Okazaki Yujiro Takeshita Junji Nishimoto Sakae Tanaka Kazuo Saita
author_sort	Satoshi Ogihara
title	Risk factors for deep surgical site infection after posterior cervical spine surgery in adults: a multicentre observational cohort study
title_short	Risk factors for deep surgical site infection after posterior cervical spine surgery in adults: a multicentre observational cohort study
title_full	Risk factors for deep surgical site infection after posterior cervical spine surgery in adults: a multicentre observational cohort study
title_fullStr	Risk factors for deep surgical site infection after posterior cervical spine surgery in adults: a multicentre observational cohort study
title_full_unstemmed	Risk factors for deep surgical site infection after posterior cervical spine surgery in adults: a multicentre observational cohort study
title_sort	risk factors for deep surgical site infection after posterior cervical spine surgery in adults: a multicentre observational cohort study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/59cbf2c0217747729b8dce5f7c13e408
work_keys_str_mv	AT satoshiogihara riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT takashiyamazaki riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT michioshiibashi riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT hirotakachikuda riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT torumaruyama riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT kotamiyoshi riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT hirohikoinanami riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT yasushioshima riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT seiichiazuma riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT naohirokawamura riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT kiyofumiyamakawa riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT nobuhirohara riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT jiromorii riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT rentarookazaki riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT yujirotakeshita riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT junjinishimoto riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT sakaetanaka riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy AT kazuosaita riskfactorsfordeepsurgicalsiteinfectionafterposteriorcervicalspinesurgeryinadultsamulticentreobservationalcohortstudy
_version_	1718391549660758016

Risk factors for deep surgical site infection after posterior cervical spine surgery in adults: a multicentre observational cohort study

Ejemplares similares