Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP

Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP

Abstract The PBAF chromatin-remodeling complexes are multi-protein machines, regulating expression of genes involved in proliferation and differentiation. PHF10 is a subunit of the PBAF essential for its association with chromatin. Mammalian PHF10 is expressed as four ubiquitous isoforms, which are...

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Autores principales: Victor V. Tatarskiy, Yuriy P. Simonov, Dmitrii S. Shcherbinin, Alexander V. Brechalov, Sofia G. Georgieva, Nataliya V. Soshnikova
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/59ced0be4ab848c393157bf2ba51b36b
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