PREVENTION OF INTESTINAL ANASTOMOTIC LEAKAGE IN CASE OF PERITONITIS (EXPERIMENTAL RESEARCH)

Background. The problem of development of postoperative complications after operations on the organs of the gastrointestinal tact is extremely important. Failure of intestinal suture, formed in the presence of peritonitis develops from 2.8 to 32 % of patients. Aim. To improve immediate outcomes in t...

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Autores principales:	Y. S. Vayner, K. V. Atamanov, E. V. Shidlovskaya
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2017
Materias:	peritonitis anastomotic leak photodynamic therapy Science Q
Acceso en línea:	https://doaj.org/article/59d34e2604f2405092000c1b559474b7
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spelling	oai:doaj.org-article:59d34e2604f2405092000c1b559474b72021-11-23T06:14:39ZPREVENTION OF INTESTINAL ANASTOMOTIC LEAKAGE IN CASE OF PERITONITIS (EXPERIMENTAL RESEARCH)2541-94202587-959610.12737/article_5a0a914de3d843.40366804https://doaj.org/article/59d34e2604f2405092000c1b559474b72017-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/497https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Background. The problem of development of postoperative complications after operations on the organs of the gastrointestinal tact is extremely important. Failure of intestinal suture, formed in the presence of peritonitis develops from 2.8 to 32 % of patients. Aim. To improve immediate outcomes in the formation of a small intestine anastomosis in conditions of purulent peritonitis. Materials and methods. We conducted immunohistochemical examination of biopsy specimens of the small intestine of 20 patients died of peritonitis and compared the area of the vascular bed in different types of intestinal wall section. The experimental operations were performed in 100 Wistar rats. On the background of established models of peritonitis we performed different variants of small bowel anastomosis, including one with the use of photodynamic therapy. On the 6th day after the surgery, animals were sacrificed, and histological examination of the anastomoses was conducted. Results. Suture strip in the section of the small intestine made at the angle of 60° is supplied substantially better than in the section made at the angle of 90°. The experiment confirmed that the suggested method of anastomosis showed the best results. Conclusion. When one forms the "end-to-end" anastomosis in the small intestine in conditions of purulent peritonitis, it is reasonable to cross the intestinal wall at the angle of 60° and to perform photodynamic therapy on the formed anastomosis.Y. S. VaynerK. V. AtamanovE. V. ShidlovskayaScientific Сentre for Family Health and Human Reproduction Problemsarticleperitonitisanastomotic leakphotodynamic therapyScienceQRUActa Biomedica Scientifica, Vol 2, Iss 6, Pp 198-203 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	peritonitis anastomotic leak photodynamic therapy Science Q
spellingShingle	peritonitis anastomotic leak photodynamic therapy Science Q Y. S. Vayner K. V. Atamanov E. V. Shidlovskaya PREVENTION OF INTESTINAL ANASTOMOTIC LEAKAGE IN CASE OF PERITONITIS (EXPERIMENTAL RESEARCH)
description	Background. The problem of development of postoperative complications after operations on the organs of the gastrointestinal tact is extremely important. Failure of intestinal suture, formed in the presence of peritonitis develops from 2.8 to 32 % of patients. Aim. To improve immediate outcomes in the formation of a small intestine anastomosis in conditions of purulent peritonitis. Materials and methods. We conducted immunohistochemical examination of biopsy specimens of the small intestine of 20 patients died of peritonitis and compared the area of the vascular bed in different types of intestinal wall section. The experimental operations were performed in 100 Wistar rats. On the background of established models of peritonitis we performed different variants of small bowel anastomosis, including one with the use of photodynamic therapy. On the 6th day after the surgery, animals were sacrificed, and histological examination of the anastomoses was conducted. Results. Suture strip in the section of the small intestine made at the angle of 60° is supplied substantially better than in the section made at the angle of 90°. The experiment confirmed that the suggested method of anastomosis showed the best results. Conclusion. When one forms the "end-to-end" anastomosis in the small intestine in conditions of purulent peritonitis, it is reasonable to cross the intestinal wall at the angle of 60° and to perform photodynamic therapy on the formed anastomosis.
format	article
author	Y. S. Vayner K. V. Atamanov E. V. Shidlovskaya
author_facet	Y. S. Vayner K. V. Atamanov E. V. Shidlovskaya
author_sort	Y. S. Vayner
title	PREVENTION OF INTESTINAL ANASTOMOTIC LEAKAGE IN CASE OF PERITONITIS (EXPERIMENTAL RESEARCH)
title_short	PREVENTION OF INTESTINAL ANASTOMOTIC LEAKAGE IN CASE OF PERITONITIS (EXPERIMENTAL RESEARCH)
title_full	PREVENTION OF INTESTINAL ANASTOMOTIC LEAKAGE IN CASE OF PERITONITIS (EXPERIMENTAL RESEARCH)
title_fullStr	PREVENTION OF INTESTINAL ANASTOMOTIC LEAKAGE IN CASE OF PERITONITIS (EXPERIMENTAL RESEARCH)
title_full_unstemmed	PREVENTION OF INTESTINAL ANASTOMOTIC LEAKAGE IN CASE OF PERITONITIS (EXPERIMENTAL RESEARCH)
title_sort	prevention of intestinal anastomotic leakage in case of peritonitis (experimental research)
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2017
url	https://doaj.org/article/59d34e2604f2405092000c1b559474b7
work_keys_str_mv	AT ysvayner preventionofintestinalanastomoticleakageincaseofperitonitisexperimentalresearch AT kvatamanov preventionofintestinalanastomoticleakageincaseofperitonitisexperimentalresearch AT evshidlovskaya preventionofintestinalanastomoticleakageincaseofperitonitisexperimentalresearch
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PREVENTION OF INTESTINAL ANASTOMOTIC LEAKAGE IN CASE OF PERITONITIS (EXPERIMENTAL RESEARCH)

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