INTERRELATION OF CHANGES IN CONCENTRATION OF LEPTIN AND ω-3 FAMILY ACIDS IN THE PLACENTA AT THE REACTIVATION OF CYTOMEGALOVIRUS INFECTION IN THE III TRIMESTER OF HUMAN PREGNANCY

A gas-chromatographic study was conducted of the content of essential polyunsaturated fatty acids of the ω-3 family: eicosapentaenoic and docosahexaenoic, an enzyme-linked immunosorbent assay of leptinin the homogenate of placental tissue in women who during the third trimester of gestation (32 week...

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Autores principales:	N. A. Ishutina, M. T. Lutsenko, I. A. Andrievskaya, N. N. Dorofienko
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2017
Materias:	leptin eicosapentaenoic acid docosahexaenoic acid placenta cytomegalovirus infection Science Q
Acceso en línea:	https://doaj.org/article/59d62dc841264769adb44fa9f424b4c2
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spelling	oai:doaj.org-article:59d62dc841264769adb44fa9f424b4c22021-11-23T06:14:38ZINTERRELATION OF CHANGES IN CONCENTRATION OF LEPTIN AND ω-3 FAMILY ACIDS IN THE PLACENTA AT THE REACTIVATION OF CYTOMEGALOVIRUS INFECTION IN THE III TRIMESTER OF HUMAN PREGNANCY2541-94202587-959610.12737/article_59fad5100b9ac7.30669050https://doaj.org/article/59d62dc841264769adb44fa9f424b4c22017-07-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/406https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596A gas-chromatographic study was conducted of the content of essential polyunsaturated fatty acids of the ω-3 family: eicosapentaenoic and docosahexaenoic, an enzyme-linked immunosorbent assay of leptinin the homogenate of placental tissue in women who during the third trimester of gestation (32 weeks) underwent reactivation of chronic cytomegalovirus infection with an antibody titer Immunoglobulin class G to cytomegalovirus 1:1600. The main group of studies was 42 placentas taken from women with cytomegalovirus infection during the period of labor. The obtained data were compared with similar parameters of the control group, which included 35 placental tissues of practically healthy women in childbirth. Based on the analysis of the data obtained, it was found that the reactivation of chronic cytomegalovirus infection in the third trimester of pregnancy (32 weeks) is associated with decrease in the concentration of ω-3 essential polyunsaturated fatty acids: eicosapentaenoic by 23 % (р < 0.01) and docosahexaenoic by 42 % (р < 0.001) with a simultaneous increase in the concentration of leptin in the placental tissue by 61 % (р < 0.001). In these conditions, the mechanisms of regulation of the transmission of fatty acids from the peripheral blood of the mother to the blood of the developing fetus through the placenta are disrupted. The contents of leptin during pregnancy is an important indicator that carries information not only about the energy reserves of the maternal organism, but also about the state of the fe^lacental complex.N. A. IshutinaM. T. LutsenkoI. A. AndrievskayaN. N. DorofienkoScientific Сentre for Family Health and Human Reproduction Problemsarticleleptineicosapentaenoic aciddocosahexaenoic acidplacentacytomegalovirus infectionScienceQRUActa Biomedica Scientifica, Vol 2, Iss 4, Pp 23-26 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	leptin eicosapentaenoic acid docosahexaenoic acid placenta cytomegalovirus infection Science Q
spellingShingle	leptin eicosapentaenoic acid docosahexaenoic acid placenta cytomegalovirus infection Science Q N. A. Ishutina M. T. Lutsenko I. A. Andrievskaya N. N. Dorofienko INTERRELATION OF CHANGES IN CONCENTRATION OF LEPTIN AND ω-3 FAMILY ACIDS IN THE PLACENTA AT THE REACTIVATION OF CYTOMEGALOVIRUS INFECTION IN THE III TRIMESTER OF HUMAN PREGNANCY
description	A gas-chromatographic study was conducted of the content of essential polyunsaturated fatty acids of the ω-3 family: eicosapentaenoic and docosahexaenoic, an enzyme-linked immunosorbent assay of leptinin the homogenate of placental tissue in women who during the third trimester of gestation (32 weeks) underwent reactivation of chronic cytomegalovirus infection with an antibody titer Immunoglobulin class G to cytomegalovirus 1:1600. The main group of studies was 42 placentas taken from women with cytomegalovirus infection during the period of labor. The obtained data were compared with similar parameters of the control group, which included 35 placental tissues of practically healthy women in childbirth. Based on the analysis of the data obtained, it was found that the reactivation of chronic cytomegalovirus infection in the third trimester of pregnancy (32 weeks) is associated with decrease in the concentration of ω-3 essential polyunsaturated fatty acids: eicosapentaenoic by 23 % (р < 0.01) and docosahexaenoic by 42 % (р < 0.001) with a simultaneous increase in the concentration of leptin in the placental tissue by 61 % (р < 0.001). In these conditions, the mechanisms of regulation of the transmission of fatty acids from the peripheral blood of the mother to the blood of the developing fetus through the placenta are disrupted. The contents of leptin during pregnancy is an important indicator that carries information not only about the energy reserves of the maternal organism, but also about the state of the fe^lacental complex.
format	article
author	N. A. Ishutina M. T. Lutsenko I. A. Andrievskaya N. N. Dorofienko
author_facet	N. A. Ishutina M. T. Lutsenko I. A. Andrievskaya N. N. Dorofienko
author_sort	N. A. Ishutina
title	INTERRELATION OF CHANGES IN CONCENTRATION OF LEPTIN AND ω-3 FAMILY ACIDS IN THE PLACENTA AT THE REACTIVATION OF CYTOMEGALOVIRUS INFECTION IN THE III TRIMESTER OF HUMAN PREGNANCY
title_short	INTERRELATION OF CHANGES IN CONCENTRATION OF LEPTIN AND ω-3 FAMILY ACIDS IN THE PLACENTA AT THE REACTIVATION OF CYTOMEGALOVIRUS INFECTION IN THE III TRIMESTER OF HUMAN PREGNANCY
title_full	INTERRELATION OF CHANGES IN CONCENTRATION OF LEPTIN AND ω-3 FAMILY ACIDS IN THE PLACENTA AT THE REACTIVATION OF CYTOMEGALOVIRUS INFECTION IN THE III TRIMESTER OF HUMAN PREGNANCY
title_fullStr	INTERRELATION OF CHANGES IN CONCENTRATION OF LEPTIN AND ω-3 FAMILY ACIDS IN THE PLACENTA AT THE REACTIVATION OF CYTOMEGALOVIRUS INFECTION IN THE III TRIMESTER OF HUMAN PREGNANCY
title_full_unstemmed	INTERRELATION OF CHANGES IN CONCENTRATION OF LEPTIN AND ω-3 FAMILY ACIDS IN THE PLACENTA AT THE REACTIVATION OF CYTOMEGALOVIRUS INFECTION IN THE III TRIMESTER OF HUMAN PREGNANCY
title_sort	interrelation of changes in concentration of leptin and ω-3 family acids in the placenta at the reactivation of cytomegalovirus infection in the iii trimester of human pregnancy
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2017
url	https://doaj.org/article/59d62dc841264769adb44fa9f424b4c2
work_keys_str_mv	AT naishutina interrelationofchangesinconcentrationofleptinandō3familyacidsintheplacentaatthereactivationofcytomegalovirusinfectionintheiiitrimesterofhumanpregnancy AT mtlutsenko interrelationofchangesinconcentrationofleptinandō3familyacidsintheplacentaatthereactivationofcytomegalovirusinfectionintheiiitrimesterofhumanpregnancy AT iaandrievskaya interrelationofchangesinconcentrationofleptinandō3familyacidsintheplacentaatthereactivationofcytomegalovirusinfectionintheiiitrimesterofhumanpregnancy AT nndorofienko interrelationofchangesinconcentrationofleptinandō3familyacidsintheplacentaatthereactivationofcytomegalovirusinfectionintheiiitrimesterofhumanpregnancy
_version_	1718417007587622912

INTERRELATION OF CHANGES IN CONCENTRATION OF LEPTIN AND ω-3 FAMILY ACIDS IN THE PLACENTA AT THE REACTIVATION OF CYTOMEGALOVIRUS INFECTION IN THE III TRIMESTER OF HUMAN PREGNANCY

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