Prostacyclin reverses platelet stress fibre formation causing platelet aggregate instability

Abstract Prostacyclin (PGI2) modulates platelet activation to regulate haemostasis. Evidence has emerged to suggest that thrombi are dynamic structures with distinct areas of differing platelet activation. It was hypothesised that PGI2 could reverse platelet spreading by actin cytoskeletal modulatio...

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Bibliographic Details
Main Authors: M. Z. Yusuf, Z. Raslan, L. Atkinson, A. Aburima, S. G. Thomas, K. M. Naseem, S. D. J. Calaminus
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/59e911bd8ed54800bd16bc7e224dceb4
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