TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh

Milk lipid secretion is a critical process for the delivery of nutrition and energy from parent to offspring. Here the authors found that TDP-43, a RNA-binding protein, is required for milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh mRNA stability.

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Autores principales:	Limin Zhao, Hao Ke, Haibo Xu, Guo-Dong Wang, Honglei Zhang, Li Zou, Shu Xiang, Mengyuan Li, Li Peng, Mingfang Zhou, Lingling Li, Lei Ao, Qin Yang, Che-Kun James Shen, Ping Yi, Lu Wang, Baowei Jiao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/59e9f9ce370048ddbeca2a29123f847a
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spelling	oai:doaj.org-article:59e9f9ce370048ddbeca2a29123f847a2021-12-02T17:33:13ZTDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh10.1038/s41467-019-14183-12041-1723https://doaj.org/article/59e9f9ce370048ddbeca2a29123f847a2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14183-1https://doaj.org/toc/2041-1723Milk lipid secretion is a critical process for the delivery of nutrition and energy from parent to offspring. Here the authors found that TDP-43, a RNA-binding protein, is required for milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh mRNA stability.Limin ZhaoHao KeHaibo XuGuo-Dong WangHonglei ZhangLi ZouShu XiangMengyuan LiLi PengMingfang ZhouLingling LiLei AoQin YangChe-Kun James ShenPing YiLu WangBaowei JiaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Limin Zhao Hao Ke Haibo Xu Guo-Dong Wang Honglei Zhang Li Zou Shu Xiang Mengyuan Li Li Peng Mingfang Zhou Lingling Li Lei Ao Qin Yang Che-Kun James Shen Ping Yi Lu Wang Baowei Jiao TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh
description	Milk lipid secretion is a critical process for the delivery of nutrition and energy from parent to offspring. Here the authors found that TDP-43, a RNA-binding protein, is required for milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh mRNA stability.
format	article
author	Limin Zhao Hao Ke Haibo Xu Guo-Dong Wang Honglei Zhang Li Zou Shu Xiang Mengyuan Li Li Peng Mingfang Zhou Lingling Li Lei Ao Qin Yang Che-Kun James Shen Ping Yi Lu Wang Baowei Jiao
author_facet	Limin Zhao Hao Ke Haibo Xu Guo-Dong Wang Honglei Zhang Li Zou Shu Xiang Mengyuan Li Li Peng Mingfang Zhou Lingling Li Lei Ao Qin Yang Che-Kun James Shen Ping Yi Lu Wang Baowei Jiao
author_sort	Limin Zhao
title	TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh
title_short	TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh
title_full	TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh
title_fullStr	TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh
title_full_unstemmed	TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh
title_sort	tdp-43 facilitates milk lipid secretion by post-transcriptional regulation of btn1a1 and xdh
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/59e9f9ce370048ddbeca2a29123f847a
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TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh

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