Nails: The Window to the Nose? Update on Yellow Nail Syndrome

Background: Yellow nail syndrome is a rare condition characterized by typical nail alterations and variable presence of lymphedema and respiratory disease. The pathogenesis is still obscure, with most of the literature deriving from case reports and few investigations. The most reported respiratory...

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Autores principales:	Laura Vollono, Marco Adriano Chessa, Antonio Bruno, Michela Starace, Aurora Alessandrini, Bianca Maria Piraccini
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2020
Materias:	yellow nail syndrome lichen planus arrested nail growth respiratory disease Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/59eeb3ee9d664ec08d2934069529d4b3
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spelling	oai:doaj.org-article:59eeb3ee9d664ec08d2934069529d4b32021-11-17T08:28:52ZNails: The Window to the Nose? Update on Yellow Nail Syndrome 10.5826/dpc.1002a312160-9381https://doaj.org/article/59eeb3ee9d664ec08d2934069529d4b32020-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/1044https://doaj.org/toc/2160-9381 Background: Yellow nail syndrome is a rare condition characterized by typical nail alterations and variable presence of lymphedema and respiratory disease. The pathogenesis is still obscure, with most of the literature deriving from case reports and few investigations. The most reported respiratory conditions associated with yellow nail syndrome are pleural effusion and bronchiectasis, whereas association with rhinosinusitis is rarer. Objectives: To describe a case of yellow nail syndrome and to provide a literature review regarding this condition, discussing pathogenetic hypothesis, associated conditions, and therapeutic options. Patients/Methods: A 49-year-old man presented with arrested growth and alterations of his nails, without any history of previous trauma or inflammation but with a severe nasal septum deviation and a history of chronic rhinosinusitis. A diagnosis of yellow nail syndrome was made. Results: Six months after undergoing rhinoseptoplasty and treatment with oral vitamin E, the patient’s nails were cured. Conclusions: This case emphasizes the role of the dermatologist in detecting systemic conditions. The correct diagnosis led to complete resolution of both nail alterations and associated respiratory condition. Laura VollonoMarco Adriano ChessaAntonio BrunoMichela StaraceAurora AlessandriniBianca Maria PiracciniMattioli1885articleyellow nail syndromelichen planusarrested nail growthrespiratory diseaseDermatologyRL1-803ENDermatology Practical & Conceptual, Vol 10, Iss 2 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	yellow nail syndrome lichen planus arrested nail growth respiratory disease Dermatology RL1-803
spellingShingle	yellow nail syndrome lichen planus arrested nail growth respiratory disease Dermatology RL1-803 Laura Vollono Marco Adriano Chessa Antonio Bruno Michela Starace Aurora Alessandrini Bianca Maria Piraccini Nails: The Window to the Nose? Update on Yellow Nail Syndrome
description	Background: Yellow nail syndrome is a rare condition characterized by typical nail alterations and variable presence of lymphedema and respiratory disease. The pathogenesis is still obscure, with most of the literature deriving from case reports and few investigations. The most reported respiratory conditions associated with yellow nail syndrome are pleural effusion and bronchiectasis, whereas association with rhinosinusitis is rarer. Objectives: To describe a case of yellow nail syndrome and to provide a literature review regarding this condition, discussing pathogenetic hypothesis, associated conditions, and therapeutic options. Patients/Methods: A 49-year-old man presented with arrested growth and alterations of his nails, without any history of previous trauma or inflammation but with a severe nasal septum deviation and a history of chronic rhinosinusitis. A diagnosis of yellow nail syndrome was made. Results: Six months after undergoing rhinoseptoplasty and treatment with oral vitamin E, the patient’s nails were cured. Conclusions: This case emphasizes the role of the dermatologist in detecting systemic conditions. The correct diagnosis led to complete resolution of both nail alterations and associated respiratory condition.
format	article
author	Laura Vollono Marco Adriano Chessa Antonio Bruno Michela Starace Aurora Alessandrini Bianca Maria Piraccini
author_facet	Laura Vollono Marco Adriano Chessa Antonio Bruno Michela Starace Aurora Alessandrini Bianca Maria Piraccini
author_sort	Laura Vollono
title	Nails: The Window to the Nose? Update on Yellow Nail Syndrome
title_short	Nails: The Window to the Nose? Update on Yellow Nail Syndrome
title_full	Nails: The Window to the Nose? Update on Yellow Nail Syndrome
title_fullStr	Nails: The Window to the Nose? Update on Yellow Nail Syndrome
title_full_unstemmed	Nails: The Window to the Nose? Update on Yellow Nail Syndrome
title_sort	nails: the window to the nose? update on yellow nail syndrome
publisher	Mattioli1885
publishDate	2020
url	https://doaj.org/article/59eeb3ee9d664ec08d2934069529d4b3
work_keys_str_mv	AT lauravollono nailsthewindowtothenoseupdateonyellownailsyndrome AT marcoadrianochessa nailsthewindowtothenoseupdateonyellownailsyndrome AT antoniobruno nailsthewindowtothenoseupdateonyellownailsyndrome AT michelastarace nailsthewindowtothenoseupdateonyellownailsyndrome AT auroraalessandrini nailsthewindowtothenoseupdateonyellownailsyndrome AT biancamariapiraccini nailsthewindowtothenoseupdateonyellownailsyndrome
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Nails: The Window to the Nose? Update on Yellow Nail Syndrome

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