BrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin

The virulence factor pyocyanin and the second messenger c-di-GMP regulate biofilm formation and antibiotic tolerance in Pseudomonas aeruginosa. Here, the authors perform structural and biochemical analyses to show that a transcriptional regulator, BrlR, acts as a receptor for both pyocyanin and c-di...

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Autores principales:	Feng Wang, Qing He, Jia Yin, Sujuan Xu, Wei Hu, Lichuan Gu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5a095ae5411145df8e95993f3d7c70f0
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spelling	oai:doaj.org-article:5a095ae5411145df8e95993f3d7c70f02021-12-02T14:39:45ZBrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin10.1038/s41467-018-05004-y2041-1723https://doaj.org/article/5a095ae5411145df8e95993f3d7c70f02018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05004-yhttps://doaj.org/toc/2041-1723The virulence factor pyocyanin and the second messenger c-di-GMP regulate biofilm formation and antibiotic tolerance in Pseudomonas aeruginosa. Here, the authors perform structural and biochemical analyses to show that a transcriptional regulator, BrlR, acts as a receptor for both pyocyanin and c-di-GMP.Feng WangQing HeJia YinSujuan XuWei HuLichuan GuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Feng Wang Qing He Jia Yin Sujuan Xu Wei Hu Lichuan Gu BrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin
description	The virulence factor pyocyanin and the second messenger c-di-GMP regulate biofilm formation and antibiotic tolerance in Pseudomonas aeruginosa. Here, the authors perform structural and biochemical analyses to show that a transcriptional regulator, BrlR, acts as a receptor for both pyocyanin and c-di-GMP.
format	article
author	Feng Wang Qing He Jia Yin Sujuan Xu Wei Hu Lichuan Gu
author_facet	Feng Wang Qing He Jia Yin Sujuan Xu Wei Hu Lichuan Gu
author_sort	Feng Wang
title	BrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin
title_short	BrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin
title_full	BrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin
title_fullStr	BrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin
title_full_unstemmed	BrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin
title_sort	brlr from pseudomonas aeruginosa is a receptor for both cyclic di-gmp and pyocyanin
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/5a095ae5411145df8e95993f3d7c70f0
work_keys_str_mv	AT fengwang brlrfrompseudomonasaeruginosaisareceptorforbothcyclicdigmpandpyocyanin AT qinghe brlrfrompseudomonasaeruginosaisareceptorforbothcyclicdigmpandpyocyanin AT jiayin brlrfrompseudomonasaeruginosaisareceptorforbothcyclicdigmpandpyocyanin AT sujuanxu brlrfrompseudomonasaeruginosaisareceptorforbothcyclicdigmpandpyocyanin AT weihu brlrfrompseudomonasaeruginosaisareceptorforbothcyclicdigmpandpyocyanin AT lichuangu brlrfrompseudomonasaeruginosaisareceptorforbothcyclicdigmpandpyocyanin
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BrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin

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