A deep learning approach to identifying immunogold particles in electron microscopy images

Abstract Electron microscopy (EM) enables high-resolution visualization of protein distributions in biological tissues. For detection, gold nanoparticles are typically used as an electron-dense marker for immunohistochemically labeled proteins. Manual annotation of gold particle labels is laborious...

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Bibliographic Details
Main Authors: Diego Jerez, Eleanor Stuart, Kylie Schmitt, Debbie Guerrero-Given, Jason M. Christie, Naomi Kamasawa, Michael S. Smirnov
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/5a0c7fe657b7450eb58edf43c22c8435
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