Structural ensemble of a glutamate transporter homologue in lipid nanodisc environment
Glutamate transporters are membrane transporters that clear the neurotransmitter L-glutamate from the synaptic cleft via a so-called elevator mechanism. Here the authors present five cryo-EM structures of the transporter homologue GltTk, which explain how substrate leakage is prevented.
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Autores principales: | Valentina Arkhipova, Albert Guskov, Dirk J. Slotboom |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/5a15e2c8a0a34570bdd68f209b8447e0 |
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