Aluminum plasmonic nanoshielding in ultraviolet inactivation of bacteria

Abstract Ultraviolet (UV) irradiation is an effective bacterial inactivation technique with broad applications in environmental disinfection. However, biomedical applications are limited due to the low selectivity, undesired inactivation of beneficial bacteria and damage of healthy tissue. New appro...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jeremy N. Kunz, Dmitri V. Voronine, Weigang Lu, Zachary Liege, Ho Wai Howard Lee, Zhenrong Zhang, Marlan O. Scully
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5a23e351db3b46e1bfa14eb4e50f2425
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5a23e351db3b46e1bfa14eb4e50f2425
record_format	dspace
spelling	oai:doaj.org-article:5a23e351db3b46e1bfa14eb4e50f24252021-12-02T16:06:36ZAluminum plasmonic nanoshielding in ultraviolet inactivation of bacteria10.1038/s41598-017-08593-82045-2322https://doaj.org/article/5a23e351db3b46e1bfa14eb4e50f24252017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-08593-8https://doaj.org/toc/2045-2322Abstract Ultraviolet (UV) irradiation is an effective bacterial inactivation technique with broad applications in environmental disinfection. However, biomedical applications are limited due to the low selectivity, undesired inactivation of beneficial bacteria and damage of healthy tissue. New approaches are needed for the protection of biological cells from UV radiation for the development of controlled treatment and improved biosensors. Aluminum plasmonics offers attractive opportunities for the control of light-matter interactions in the UV range, which have not yet been explored in microbiology. Here, we investigate the effects of aluminum nanoparticles (Al NPs) prepared by sonication of aluminum foil on the UVC inactivation of E. coli bacteria and demonstrate a new radiation protection mechanism via plasmonic nanoshielding. We observe direct interaction of the bacterial cells with Al NPs and elucidate the nanoshielding mechanism via UV plasmonic resonance and nanotailing effects. Concentration and wavelength dependence studies reveal the role and range of control parameters for regulating the radiation dosage to achieve effective UVC protection. Our results provide a step towards developing improved radiation-based bacterial treatments.Jeremy N. KunzDmitri V. VoronineWeigang LuZachary LiegeHo Wai Howard LeeZhenrong ZhangMarlan O. ScullyNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jeremy N. Kunz Dmitri V. Voronine Weigang Lu Zachary Liege Ho Wai Howard Lee Zhenrong Zhang Marlan O. Scully Aluminum plasmonic nanoshielding in ultraviolet inactivation of bacteria
description	Abstract Ultraviolet (UV) irradiation is an effective bacterial inactivation technique with broad applications in environmental disinfection. However, biomedical applications are limited due to the low selectivity, undesired inactivation of beneficial bacteria and damage of healthy tissue. New approaches are needed for the protection of biological cells from UV radiation for the development of controlled treatment and improved biosensors. Aluminum plasmonics offers attractive opportunities for the control of light-matter interactions in the UV range, which have not yet been explored in microbiology. Here, we investigate the effects of aluminum nanoparticles (Al NPs) prepared by sonication of aluminum foil on the UVC inactivation of E. coli bacteria and demonstrate a new radiation protection mechanism via plasmonic nanoshielding. We observe direct interaction of the bacterial cells with Al NPs and elucidate the nanoshielding mechanism via UV plasmonic resonance and nanotailing effects. Concentration and wavelength dependence studies reveal the role and range of control parameters for regulating the radiation dosage to achieve effective UVC protection. Our results provide a step towards developing improved radiation-based bacterial treatments.
format	article
author	Jeremy N. Kunz Dmitri V. Voronine Weigang Lu Zachary Liege Ho Wai Howard Lee Zhenrong Zhang Marlan O. Scully
author_facet	Jeremy N. Kunz Dmitri V. Voronine Weigang Lu Zachary Liege Ho Wai Howard Lee Zhenrong Zhang Marlan O. Scully
author_sort	Jeremy N. Kunz
title	Aluminum plasmonic nanoshielding in ultraviolet inactivation of bacteria
title_short	Aluminum plasmonic nanoshielding in ultraviolet inactivation of bacteria
title_full	Aluminum plasmonic nanoshielding in ultraviolet inactivation of bacteria
title_fullStr	Aluminum plasmonic nanoshielding in ultraviolet inactivation of bacteria
title_full_unstemmed	Aluminum plasmonic nanoshielding in ultraviolet inactivation of bacteria
title_sort	aluminum plasmonic nanoshielding in ultraviolet inactivation of bacteria
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/5a23e351db3b46e1bfa14eb4e50f2425
work_keys_str_mv	AT jeremynkunz aluminumplasmonicnanoshieldinginultravioletinactivationofbacteria AT dmitrivvoronine aluminumplasmonicnanoshieldinginultravioletinactivationofbacteria AT weiganglu aluminumplasmonicnanoshieldinginultravioletinactivationofbacteria AT zacharyliege aluminumplasmonicnanoshieldinginultravioletinactivationofbacteria AT howaihowardlee aluminumplasmonicnanoshieldinginultravioletinactivationofbacteria AT zhenrongzhang aluminumplasmonicnanoshieldinginultravioletinactivationofbacteria AT marlanoscully aluminumplasmonicnanoshieldinginultravioletinactivationofbacteria
_version_	1718384962196996096

Aluminum plasmonic nanoshielding in ultraviolet inactivation of bacteria

Ejemplares similares