Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts.

<h4>Background</h4>Oncogene activation plays a role in metabolic reprogramming of cancer cells. We have previously shown that K-ras transformed fibroblasts have a stronger dependence on glycolysis and a reduced oxidative phosphorylation ability as compared to their normal counterparts. A...

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Bibliographic Details
Main Authors: Daniela Gaglio, Chiara Soldati, Marco Vanoni, Lilia Alberghina, Ferdinando Chiaradonna
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
Subjects:
R
Q
Online Access:https://doaj.org/article/5a27f0d3f1004449abb3f8efb4950b95
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