Cervical Cancer and Fertility-Sparing Treatment

Radical hysterectomy with pelvic node dissection is the standard treatment for early-stage cervical cancer. However, the latter can be diagnosed at a young age when patients have not yet achieved their pregnancy plans. Dargent first described the vaginal radical trachelectomy for patients with tumor...

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Autores principales:	François Zaccarini, Claire Sanson, Amandine Maulard, Stéphanie Schérier, Alexandra Leary, Patricia Pautier, Cyrus Chargari, Catherine Genestie, Sébastien Gouy, Philippe Morice
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	early-stage cervical cancer fertility-sparing treatment conization trachelectomy Medicine R
Acceso en línea:	https://doaj.org/article/5a3562a2667249d8b9a3cab9a5b97f74
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spelling	oai:doaj.org-article:5a3562a2667249d8b9a3cab9a5b97f742021-11-11T17:29:46ZCervical Cancer and Fertility-Sparing Treatment10.3390/jcm102148252077-0383https://doaj.org/article/5a3562a2667249d8b9a3cab9a5b97f742021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/4825https://doaj.org/toc/2077-0383Radical hysterectomy with pelvic node dissection is the standard treatment for early-stage cervical cancer. However, the latter can be diagnosed at a young age when patients have not yet achieved their pregnancy plans. Dargent first described the vaginal radical trachelectomy for patients with tumors <2 cm. It has since been described a population of low risk of recurrence: patients with tumors <2 cm, without deep stromal infiltration, without lymphovascular invasion (LVSI), and with negative lymph nodes. These patients can benefit from a less radical surgery such as conization or simple trachelectomy with the evaluation of the pelvic node status. Tumors larger than 2 cm have a higher risk of recurrence and their treatment is a challenge. There are currently two options for these patients: abdominal radical trachelectomy or neoadjuvant chemotherapy (NACT), followed by fertility-sparing surgery. All patients who wish to preserve their fertility must be referred to expert centers.François ZaccariniClaire SansonAmandine MaulardStéphanie SchérierAlexandra LearyPatricia PautierCyrus ChargariCatherine GenestieSébastien GouyPhilippe MoriceMDPI AGarticleearly-stage cervical cancerfertility-sparing treatmentconizationtrachelectomyMedicineRENJournal of Clinical Medicine, Vol 10, Iss 4825, p 4825 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	early-stage cervical cancer fertility-sparing treatment conization trachelectomy Medicine R
spellingShingle	early-stage cervical cancer fertility-sparing treatment conization trachelectomy Medicine R François Zaccarini Claire Sanson Amandine Maulard Stéphanie Schérier Alexandra Leary Patricia Pautier Cyrus Chargari Catherine Genestie Sébastien Gouy Philippe Morice Cervical Cancer and Fertility-Sparing Treatment
description	Radical hysterectomy with pelvic node dissection is the standard treatment for early-stage cervical cancer. However, the latter can be diagnosed at a young age when patients have not yet achieved their pregnancy plans. Dargent first described the vaginal radical trachelectomy for patients with tumors <2 cm. It has since been described a population of low risk of recurrence: patients with tumors <2 cm, without deep stromal infiltration, without lymphovascular invasion (LVSI), and with negative lymph nodes. These patients can benefit from a less radical surgery such as conization or simple trachelectomy with the evaluation of the pelvic node status. Tumors larger than 2 cm have a higher risk of recurrence and their treatment is a challenge. There are currently two options for these patients: abdominal radical trachelectomy or neoadjuvant chemotherapy (NACT), followed by fertility-sparing surgery. All patients who wish to preserve their fertility must be referred to expert centers.
format	article
author	François Zaccarini Claire Sanson Amandine Maulard Stéphanie Schérier Alexandra Leary Patricia Pautier Cyrus Chargari Catherine Genestie Sébastien Gouy Philippe Morice
author_facet	François Zaccarini Claire Sanson Amandine Maulard Stéphanie Schérier Alexandra Leary Patricia Pautier Cyrus Chargari Catherine Genestie Sébastien Gouy Philippe Morice
author_sort	François Zaccarini
title	Cervical Cancer and Fertility-Sparing Treatment
title_short	Cervical Cancer and Fertility-Sparing Treatment
title_full	Cervical Cancer and Fertility-Sparing Treatment
title_fullStr	Cervical Cancer and Fertility-Sparing Treatment
title_full_unstemmed	Cervical Cancer and Fertility-Sparing Treatment
title_sort	cervical cancer and fertility-sparing treatment
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/5a3562a2667249d8b9a3cab9a5b97f74
work_keys_str_mv	AT francoiszaccarini cervicalcancerandfertilitysparingtreatment AT clairesanson cervicalcancerandfertilitysparingtreatment AT amandinemaulard cervicalcancerandfertilitysparingtreatment AT stephaniescherier cervicalcancerandfertilitysparingtreatment AT alexandraleary cervicalcancerandfertilitysparingtreatment AT patriciapautier cervicalcancerandfertilitysparingtreatment AT cyruschargari cervicalcancerandfertilitysparingtreatment AT catherinegenestie cervicalcancerandfertilitysparingtreatment AT sebastiengouy cervicalcancerandfertilitysparingtreatment AT philippemorice cervicalcancerandfertilitysparingtreatment
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Cervical Cancer and Fertility-Sparing Treatment

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