Silica-coated magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate identified using integrated omics

Abstract Background Nanoparticles have been utilized in brain research and therapeutics, including imaging, diagnosis, and drug delivery, owing to their versatile properties compared to bulk materials. However, exposure to nanoparticles leads to their accumulation in the brain, but drug development...

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Autores principales:	Tae Hwan Shin, Balachandran Manavalan, Da Yeon Lee, Shaherin Basith, Chan Seo, Man Jeong Paik, Sang-Wook Kim, Haewoon Seo, Ju Yeon Lee, Jin Young Kim, A Young Kim, Jee Min Chung, Eun Joo Baik, Seong Ho Kang, Dong-Kug Choi, Yup Kang, M. Maral Mouradian, Gwang Lee
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Silica-coated magnetic nanoparticles Nanotoxicity Integrated omics Microglia Machine learning Toxicology. Poisons RA1190-1270 Industrial hygiene. Industrial welfare HD7260-7780.8
Acceso en línea:	https://doaj.org/article/5a3f65fab7ff4f3ea7bfc98a0d28a485
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Silica-coated magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate identified using integrated omics

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