Silica-coated magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate identified using integrated omics

Silica-coated magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate identified using integrated omics

Abstract Background Nanoparticles have been utilized in brain research and therapeutics, including imaging, diagnosis, and drug delivery, owing to their versatile properties compared to bulk materials. However, exposure to nanoparticles leads to their accumulation in the brain, but drug development...

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Main Authors: Tae Hwan Shin, Balachandran Manavalan, Da Yeon Lee, Shaherin Basith, Chan Seo, Man Jeong Paik, Sang-Wook Kim, Haewoon Seo, Ju Yeon Lee, Jin Young Kim, A Young Kim, Jee Min Chung, Eun Joo Baik, Seong Ho Kang, Dong-Kug Choi, Yup Kang, M. Maral Mouradian, Gwang Lee
Format: article
Language:EN
Published: BMC 2021
Subjects:
Silica-coated magnetic nanoparticles
Nanotoxicity
Integrated omics
Microglia
Machine learning
Toxicology. Poisons
RA1190-1270
Industrial hygiene. Industrial welfare
HD7260-7780.8
Online Access:https://doaj.org/article/5a3f65fab7ff4f3ea7bfc98a0d28a485
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https://doaj.org/article/5a3f65fab7ff4f3ea7bfc98a0d28a485

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