Chromosomal coordination and differential structure of asynchronous replicating regions

Most regions of the mammalian genome replicate both alleles in a synchronous manner, but some loci have been found to replicate asynchronously and the time of replication of each allele is different. Here the authors, by employing clonal mouse cells from a hybrid strain chart replication timing over...

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Autores principales:	Britny Blumenfeld, Hagit Masika, Marganit Farago, Yishai Yehuda, Lamia Halaseh, Oriya Vardi, Rachel Rapoport, Rena Levin-Klein, Howard Cedar, Yehudit Bergman, Itamar Simon
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5a44785bc8d24207acd6f75995d67d94
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spelling	oai:doaj.org-article:5a44785bc8d24207acd6f75995d67d942021-12-02T14:03:40ZChromosomal coordination and differential structure of asynchronous replicating regions10.1038/s41467-021-21348-42041-1723https://doaj.org/article/5a44785bc8d24207acd6f75995d67d942021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21348-4https://doaj.org/toc/2041-1723Most regions of the mammalian genome replicate both alleles in a synchronous manner, but some loci have been found to replicate asynchronously and the time of replication of each allele is different. Here the authors, by employing clonal mouse cells from a hybrid strain chart replication timing over the entire genome, using polymorphisms to distinguish between the paternal and maternal alleles.Britny BlumenfeldHagit MasikaMarganit FaragoYishai YehudaLamia HalasehOriya VardiRachel RapoportRena Levin-KleinHoward CedarYehudit BergmanItamar SimonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Britny Blumenfeld Hagit Masika Marganit Farago Yishai Yehuda Lamia Halaseh Oriya Vardi Rachel Rapoport Rena Levin-Klein Howard Cedar Yehudit Bergman Itamar Simon Chromosomal coordination and differential structure of asynchronous replicating regions
description	Most regions of the mammalian genome replicate both alleles in a synchronous manner, but some loci have been found to replicate asynchronously and the time of replication of each allele is different. Here the authors, by employing clonal mouse cells from a hybrid strain chart replication timing over the entire genome, using polymorphisms to distinguish between the paternal and maternal alleles.
format	article
author	Britny Blumenfeld Hagit Masika Marganit Farago Yishai Yehuda Lamia Halaseh Oriya Vardi Rachel Rapoport Rena Levin-Klein Howard Cedar Yehudit Bergman Itamar Simon
author_facet	Britny Blumenfeld Hagit Masika Marganit Farago Yishai Yehuda Lamia Halaseh Oriya Vardi Rachel Rapoport Rena Levin-Klein Howard Cedar Yehudit Bergman Itamar Simon
author_sort	Britny Blumenfeld
title	Chromosomal coordination and differential structure of asynchronous replicating regions
title_short	Chromosomal coordination and differential structure of asynchronous replicating regions
title_full	Chromosomal coordination and differential structure of asynchronous replicating regions
title_fullStr	Chromosomal coordination and differential structure of asynchronous replicating regions
title_full_unstemmed	Chromosomal coordination and differential structure of asynchronous replicating regions
title_sort	chromosomal coordination and differential structure of asynchronous replicating regions
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5a44785bc8d24207acd6f75995d67d94
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Chromosomal coordination and differential structure of asynchronous replicating regions

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