Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning

The authors show in Nematostella that the more orally expressed β-catenin targets repress the more aborally expressed β-catenin targets, thus patterning the oral-aboral axis. This likely represents the common mechanism of β-catenin-dependent axial patterning shared by Cnidaria and Bilateria.

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Detalles Bibliográficos
Autores principales: Tatiana Lebedeva, Andrew J. Aman, Thomas Graf, Isabell Niedermoser, Bob Zimmermann, Yulia Kraus, Magdalena Schatka, Adrien Demilly, Ulrich Technau, Grigory Genikhovich
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5a46d86e69d744169a26a40510649b01
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Sumario:The authors show in Nematostella that the more orally expressed β-catenin targets repress the more aborally expressed β-catenin targets, thus patterning the oral-aboral axis. This likely represents the common mechanism of β-catenin-dependent axial patterning shared by Cnidaria and Bilateria.