Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning

The authors show in Nematostella that the more orally expressed β-catenin targets repress the more aborally expressed β-catenin targets, thus patterning the oral-aboral axis. This likely represents the common mechanism of β-catenin-dependent axial patterning shared by Cnidaria and Bilateria.

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Autores principales: Tatiana Lebedeva, Andrew J. Aman, Thomas Graf, Isabell Niedermoser, Bob Zimmermann, Yulia Kraus, Magdalena Schatka, Adrien Demilly, Ulrich Technau, Grigory Genikhovich
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5a46d86e69d744169a26a40510649b01
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spelling oai:doaj.org-article:5a46d86e69d744169a26a40510649b012021-12-02T16:31:43ZCnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning10.1038/s41467-021-24346-82041-1723https://doaj.org/article/5a46d86e69d744169a26a40510649b012021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24346-8https://doaj.org/toc/2041-1723The authors show in Nematostella that the more orally expressed β-catenin targets repress the more aborally expressed β-catenin targets, thus patterning the oral-aboral axis. This likely represents the common mechanism of β-catenin-dependent axial patterning shared by Cnidaria and Bilateria.Tatiana LebedevaAndrew J. AmanThomas GrafIsabell NiedermoserBob ZimmermannYulia KrausMagdalena SchatkaAdrien DemillyUlrich TechnauGrigory GenikhovichNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Tatiana Lebedeva
Andrew J. Aman
Thomas Graf
Isabell Niedermoser
Bob Zimmermann
Yulia Kraus
Magdalena Schatka
Adrien Demilly
Ulrich Technau
Grigory Genikhovich
Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning
description The authors show in Nematostella that the more orally expressed β-catenin targets repress the more aborally expressed β-catenin targets, thus patterning the oral-aboral axis. This likely represents the common mechanism of β-catenin-dependent axial patterning shared by Cnidaria and Bilateria.
format article
author Tatiana Lebedeva
Andrew J. Aman
Thomas Graf
Isabell Niedermoser
Bob Zimmermann
Yulia Kraus
Magdalena Schatka
Adrien Demilly
Ulrich Technau
Grigory Genikhovich
author_facet Tatiana Lebedeva
Andrew J. Aman
Thomas Graf
Isabell Niedermoser
Bob Zimmermann
Yulia Kraus
Magdalena Schatka
Adrien Demilly
Ulrich Technau
Grigory Genikhovich
author_sort Tatiana Lebedeva
title Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning
title_short Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning
title_full Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning
title_fullStr Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning
title_full_unstemmed Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning
title_sort cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5a46d86e69d744169a26a40510649b01
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