Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning
The authors show in Nematostella that the more orally expressed β-catenin targets repress the more aborally expressed β-catenin targets, thus patterning the oral-aboral axis. This likely represents the common mechanism of β-catenin-dependent axial patterning shared by Cnidaria and Bilateria.
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2021
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oai:doaj.org-article:5a46d86e69d744169a26a40510649b012021-12-02T16:31:43ZCnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning10.1038/s41467-021-24346-82041-1723https://doaj.org/article/5a46d86e69d744169a26a40510649b012021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24346-8https://doaj.org/toc/2041-1723The authors show in Nematostella that the more orally expressed β-catenin targets repress the more aborally expressed β-catenin targets, thus patterning the oral-aboral axis. This likely represents the common mechanism of β-catenin-dependent axial patterning shared by Cnidaria and Bilateria.Tatiana LebedevaAndrew J. AmanThomas GrafIsabell NiedermoserBob ZimmermannYulia KrausMagdalena SchatkaAdrien DemillyUlrich TechnauGrigory GenikhovichNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
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Science Q Tatiana Lebedeva Andrew J. Aman Thomas Graf Isabell Niedermoser Bob Zimmermann Yulia Kraus Magdalena Schatka Adrien Demilly Ulrich Technau Grigory Genikhovich Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning |
description |
The authors show in Nematostella that the more orally expressed β-catenin targets repress the more aborally expressed β-catenin targets, thus patterning the oral-aboral axis. This likely represents the common mechanism of β-catenin-dependent axial patterning shared by Cnidaria and Bilateria. |
format |
article |
author |
Tatiana Lebedeva Andrew J. Aman Thomas Graf Isabell Niedermoser Bob Zimmermann Yulia Kraus Magdalena Schatka Adrien Demilly Ulrich Technau Grigory Genikhovich |
author_facet |
Tatiana Lebedeva Andrew J. Aman Thomas Graf Isabell Niedermoser Bob Zimmermann Yulia Kraus Magdalena Schatka Adrien Demilly Ulrich Technau Grigory Genikhovich |
author_sort |
Tatiana Lebedeva |
title |
Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning |
title_short |
Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning |
title_full |
Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning |
title_fullStr |
Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning |
title_full_unstemmed |
Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning |
title_sort |
cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/5a46d86e69d744169a26a40510649b01 |
work_keys_str_mv |
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1718383873238237184 |