Inhibition of RPS6K reveals context-dependent Akt activity in luminal breast cancer cells.
Aberrant signaling through insulin (Ins) and insulin-like growth factor I (IGF1) receptors contribute to the risk and advancement of many cancer types by activating cell survival cascades. Similarities between these pathways have thus far prevented the development of pharmacological interventions th...
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Autores principales: | Cemal Erdem, Adrian V Lee, D Lansing Taylor, Timothy R Lezon |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/5a50932ee04e4320af6e668981cb0eb3 |
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