A multicentre validation study of the diagnostic value of plasma neurofilament light

A multicentre validation study of the diagnostic value of plasma neurofilament light

Cerebrospinal fluid neurofilament light (NfL) is a biomarker for neurodegeneration that can also be assessed in blood. Here the authors show in a validation study the potential for plasma NfL as a biomarker for several neurodegenerative diseases.

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Autores principales: Nicholas J. Ashton, Shorena Janelidze, Ahmad Al Khleifat, Antoine Leuzy, Emma L. van der Ende, Thomas K. Karikari, Andrea L. Benedet, Tharick A. Pascoal, Alberto Lleó, Lucilla Parnetti, Daniela Galimberti, Laura Bonanni, Andrea Pilotto, Alessandro Padovani, Jan Lycke, Lenka Novakova, Markus Axelsson, Latha Velayudhan, Gil D. Rabinovici, Bruce Miller, Carmine Pariante, Naghmeh Nikkheslat, Susan M. Resnick, Madhav Thambisetty, Michael Schöll, Gorka Fernández-Eulate, Francisco J. Gil-Bea, Adolfo López de Munain, Ammar Al-Chalabi, Pedro Rosa-Neto, Andre Strydom, Per Svenningsson, Erik Stomrud, Alexander Santillo, Dag Aarsland, John C. van Swieten, Sebastian Palmqvist, Henrik Zetterberg, Kaj Blennow, Abdul Hye, Oskar Hansson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5a53b0a732414b4ca05246e46c25baa3
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spelling oai:doaj.org-article:5a53b0a732414b4ca05246e46c25baa32021-12-02T18:06:34ZA multicentre validation study of the diagnostic value of plasma neurofilament light10.1038/s41467-021-23620-z2041-1723https://doaj.org/article/5a53b0a732414b4ca05246e46c25baa32021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23620-zhttps://doaj.org/toc/2041-1723Cerebrospinal fluid neurofilament light (NfL) is a biomarker for neurodegeneration that can also be assessed in blood. Here the authors show in a validation study the potential for plasma NfL as a biomarker for several neurodegenerative diseases.Nicholas J. AshtonShorena JanelidzeAhmad Al KhleifatAntoine LeuzyEmma L. van der EndeThomas K. KarikariAndrea L. BenedetTharick A. PascoalAlberto LleóLucilla ParnettiDaniela GalimbertiLaura BonanniAndrea PilottoAlessandro PadovaniJan LyckeLenka NovakovaMarkus AxelssonLatha VelayudhanGil D. RabinoviciBruce MillerCarmine ParianteNaghmeh NikkheslatSusan M. ResnickMadhav ThambisettyMichael SchöllGorka Fernández-EulateFrancisco J. Gil-BeaAdolfo López de MunainAmmar Al-ChalabiPedro Rosa-NetoAndre StrydomPer SvenningssonErik StomrudAlexander SantilloDag AarslandJohn C. van SwietenSebastian PalmqvistHenrik ZetterbergKaj BlennowAbdul HyeOskar HanssonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nicholas J. Ashton
Shorena Janelidze
Ahmad Al Khleifat
Antoine Leuzy
Emma L. van der Ende
Thomas K. Karikari
Andrea L. Benedet
Tharick A. Pascoal
Alberto Lleó
Lucilla Parnetti
Daniela Galimberti
Laura Bonanni
Andrea Pilotto
Alessandro Padovani
Jan Lycke
Lenka Novakova
Markus Axelsson
Latha Velayudhan
Gil D. Rabinovici
Bruce Miller
Carmine Pariante
Naghmeh Nikkheslat
Susan M. Resnick
Madhav Thambisetty
Michael Schöll
Gorka Fernández-Eulate
Francisco J. Gil-Bea
Adolfo López de Munain
Ammar Al-Chalabi
Pedro Rosa-Neto
Andre Strydom
Per Svenningsson
Erik Stomrud
Alexander Santillo
Dag Aarsland
John C. van Swieten
Sebastian Palmqvist
Henrik Zetterberg
Kaj Blennow
Abdul Hye
Oskar Hansson
A multicentre validation study of the diagnostic value of plasma neurofilament light
description Cerebrospinal fluid neurofilament light (NfL) is a biomarker for neurodegeneration that can also be assessed in blood. Here the authors show in a validation study the potential for plasma NfL as a biomarker for several neurodegenerative diseases.
format article
author Nicholas J. Ashton
Shorena Janelidze
Ahmad Al Khleifat
Antoine Leuzy
Emma L. van der Ende
Thomas K. Karikari
Andrea L. Benedet
Tharick A. Pascoal
Alberto Lleó
Lucilla Parnetti
Daniela Galimberti
Laura Bonanni
Andrea Pilotto
Alessandro Padovani
Jan Lycke
Lenka Novakova
Markus Axelsson
Latha Velayudhan
Gil D. Rabinovici
Bruce Miller
Carmine Pariante
Naghmeh Nikkheslat
Susan M. Resnick
Madhav Thambisetty
Michael Schöll
Gorka Fernández-Eulate
Francisco J. Gil-Bea
Adolfo López de Munain
Ammar Al-Chalabi
Pedro Rosa-Neto
Andre Strydom
Per Svenningsson
Erik Stomrud
Alexander Santillo
Dag Aarsland
John C. van Swieten
Sebastian Palmqvist
Henrik Zetterberg
Kaj Blennow
Abdul Hye
Oskar Hansson
author_facet Nicholas J. Ashton
Shorena Janelidze
Ahmad Al Khleifat
Antoine Leuzy
Emma L. van der Ende
Thomas K. Karikari
Andrea L. Benedet
Tharick A. Pascoal
Alberto Lleó
Lucilla Parnetti
Daniela Galimberti
Laura Bonanni
Andrea Pilotto
Alessandro Padovani
Jan Lycke
Lenka Novakova
Markus Axelsson
Latha Velayudhan
Gil D. Rabinovici
Bruce Miller
Carmine Pariante
Naghmeh Nikkheslat
Susan M. Resnick
Madhav Thambisetty
Michael Schöll
Gorka Fernández-Eulate
Francisco J. Gil-Bea
Adolfo López de Munain
Ammar Al-Chalabi
Pedro Rosa-Neto
Andre Strydom
Per Svenningsson
Erik Stomrud
Alexander Santillo
Dag Aarsland
John C. van Swieten
Sebastian Palmqvist
Henrik Zetterberg
Kaj Blennow
Abdul Hye
Oskar Hansson
author_sort Nicholas J. Ashton
title A multicentre validation study of the diagnostic value of plasma neurofilament light
title_short A multicentre validation study of the diagnostic value of plasma neurofilament light
title_full A multicentre validation study of the diagnostic value of plasma neurofilament light
title_fullStr A multicentre validation study of the diagnostic value of plasma neurofilament light
title_full_unstemmed A multicentre validation study of the diagnostic value of plasma neurofilament light
title_sort multicentre validation study of the diagnostic value of plasma neurofilament light
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5a53b0a732414b4ca05246e46c25baa3
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