ASSOCIATION OF HORMONE RECEPTORS WITH RISK FACTORS AMONG BREAST CANCER PATIENTS

Objective: To compare the risk factors with estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2) status of breast cancer patients. Study Design: Cross sectional comparative study. Place and Duration of Study: This study was carried out in Multidis...

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Autores principales:	Ummara Aslam, Sarah Sadiq, Naseem Irshad, Ambreen Sadiq, Rabia Hamid
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	breast cancer estrogen receptor (er) risk factors human epidermal growth factor receptor 2 (her2) progesterone receptor (pr) Medicine R Medicine (General) R5-920
Acceso en línea:	https://doi.org/10.51253/pafmj.v71iSuppl-1.4589 https://doaj.org/article/5a5440731aaa46feb0d914d62422f3da
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spelling	oai:doaj.org-article:5a5440731aaa46feb0d914d62422f3da2021-12-02T19:11:53ZASSOCIATION OF HORMONE RECEPTORS WITH RISK FACTORS AMONG BREAST CANCER PATIENTShttps://doi.org/10.51253/pafmj.v71iSuppl-1.45890030-96482411-8842https://doaj.org/article/5a5440731aaa46feb0d914d62422f3da2021-01-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/4589https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare the risk factors with estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2) status of breast cancer patients. Study Design: Cross sectional comparative study. Place and Duration of Study: This study was carried out in Multidisciplinary Lab-1 of Army Medical College, National University of Medical Sciences, Rawalpindi, in collaboration with Department of Pathology of Army Medical College, NUMS Rawalpindi, from Jan 2019 to Jan 2020. Methodology: A total of 50 individuals including radiologically diagnosed cases of breast cancer with different stages and 10 healthy controls without cancer. Patients with any co-morbidity were excluded. Participant’s sample was collected and subjected to ER, PR and HER2 estimation. Other factors i.e. age, gender, marital status, breast feeding, menopause status, side of the breast affected were all taken into consideration. Results: Patients characteristics showed that the mean age, marital and menopause status were linked with breast cancer. The data showed that hormone receptors i.e., ER (p=0.0001), PR (p=0.0002) and HER2 (p=0.0001) were positive among most of the cancer patients as compared to the healthy subjects without cancer. There were no association found between age and hormone receptors. Marital status, breast feeding, menopause and side of breasts involved also had no association with hormone receptors. Conclusion: No significant association found between risk factors and hormone recpetors status of breast cancer patients in our population.Ummara AslamSarah SadiqNaseem IrshadAmbreen SadiqRabia HamidArmy Medical College Rawalpindiarticlebreast cancerestrogen receptor (er)risk factorshuman epidermal growth factor receptor 2 (her2)progesterone receptor (pr)MedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss SUPPL-1, Pp 118-122 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	breast cancer estrogen receptor (er) risk factors human epidermal growth factor receptor 2 (her2) progesterone receptor (pr) Medicine R Medicine (General) R5-920
spellingShingle	breast cancer estrogen receptor (er) risk factors human epidermal growth factor receptor 2 (her2) progesterone receptor (pr) Medicine R Medicine (General) R5-920 Ummara Aslam Sarah Sadiq Naseem Irshad Ambreen Sadiq Rabia Hamid ASSOCIATION OF HORMONE RECEPTORS WITH RISK FACTORS AMONG BREAST CANCER PATIENTS
description	Objective: To compare the risk factors with estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2) status of breast cancer patients. Study Design: Cross sectional comparative study. Place and Duration of Study: This study was carried out in Multidisciplinary Lab-1 of Army Medical College, National University of Medical Sciences, Rawalpindi, in collaboration with Department of Pathology of Army Medical College, NUMS Rawalpindi, from Jan 2019 to Jan 2020. Methodology: A total of 50 individuals including radiologically diagnosed cases of breast cancer with different stages and 10 healthy controls without cancer. Patients with any co-morbidity were excluded. Participant’s sample was collected and subjected to ER, PR and HER2 estimation. Other factors i.e. age, gender, marital status, breast feeding, menopause status, side of the breast affected were all taken into consideration. Results: Patients characteristics showed that the mean age, marital and menopause status were linked with breast cancer. The data showed that hormone receptors i.e., ER (p=0.0001), PR (p=0.0002) and HER2 (p=0.0001) were positive among most of the cancer patients as compared to the healthy subjects without cancer. There were no association found between age and hormone receptors. Marital status, breast feeding, menopause and side of breasts involved also had no association with hormone receptors. Conclusion: No significant association found between risk factors and hormone recpetors status of breast cancer patients in our population.
format	article
author	Ummara Aslam Sarah Sadiq Naseem Irshad Ambreen Sadiq Rabia Hamid
author_facet	Ummara Aslam Sarah Sadiq Naseem Irshad Ambreen Sadiq Rabia Hamid
author_sort	Ummara Aslam
title	ASSOCIATION OF HORMONE RECEPTORS WITH RISK FACTORS AMONG BREAST CANCER PATIENTS
title_short	ASSOCIATION OF HORMONE RECEPTORS WITH RISK FACTORS AMONG BREAST CANCER PATIENTS
title_full	ASSOCIATION OF HORMONE RECEPTORS WITH RISK FACTORS AMONG BREAST CANCER PATIENTS
title_fullStr	ASSOCIATION OF HORMONE RECEPTORS WITH RISK FACTORS AMONG BREAST CANCER PATIENTS
title_full_unstemmed	ASSOCIATION OF HORMONE RECEPTORS WITH RISK FACTORS AMONG BREAST CANCER PATIENTS
title_sort	association of hormone receptors with risk factors among breast cancer patients
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doi.org/10.51253/pafmj.v71iSuppl-1.4589 https://doaj.org/article/5a5440731aaa46feb0d914d62422f3da
work_keys_str_mv	AT ummaraaslam associationofhormonereceptorswithriskfactorsamongbreastcancerpatients AT sarahsadiq associationofhormonereceptorswithriskfactorsamongbreastcancerpatients AT naseemirshad associationofhormonereceptorswithriskfactorsamongbreastcancerpatients AT ambreensadiq associationofhormonereceptorswithriskfactorsamongbreastcancerpatients AT rabiahamid associationofhormonereceptorswithriskfactorsamongbreastcancerpatients
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ASSOCIATION OF HORMONE RECEPTORS WITH RISK FACTORS AMONG BREAST CANCER PATIENTS

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