A basal level of γ-linolenic acid depletes Ca2+ stores and induces endoplasmic reticulum and oxidative stresses to cause death of breast cancer BT-474 cells

Gamma-linolenic acid (GLA), a natural fatty acid obtained from oils of various vegetables and seeds, has been demonstrated as an anticancer agent. In this work, we investigated the anticancer effects of GLA on breast cancer BT-474 cells. GLA at 30 μM, a concentration reportedly within the range of c...

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Bibliographic Details
Main Authors: Cing-Yu Chen, Cheng-Hsun Wu, King-Chuen Wu, Lian-Ru Shiao, Chin-Min Chuang, Yuk-Man Leung, Louis W C Chow
Format: article
Language:EN
Published: Wolters Kluwer Medknow Publications 2021
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Online Access:https://doaj.org/article/5a55c058ae314ae9ae0727b140c2d0c2
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