Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation

Caveolae are plasma membrane invaginations playing crucial functions, like signal transduction and mechanoprotection. Here, the authors show that caveolae contribute to skin pigmentation by integrating the biochemical and mechanical response of epidermal melanocytes to extracellular cues.

Guardado en:

Detalles Bibliográficos
Autores principales:	Lia Domingues, Ilse Hurbain, Floriane Gilles-Marsens, Julia Sirés-Campos, Nathalie André, Melissa Dewulf, Maryse Romao, Christine Viaris de Lesegno, Anne-Sophie Macé, Cédric Blouin, Christelle Guéré, Katell Vié, Graça Raposo, Christophe Lamaze, Cédric Delevoye
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5a5abd8e146f49ffb2ee2052801b4b84
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5a5abd8e146f49ffb2ee2052801b4b84
record_format	dspace
spelling	oai:doaj.org-article:5a5abd8e146f49ffb2ee2052801b4b842021-12-02T17:47:34ZCoupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation10.1038/s41467-020-16738-z2041-1723https://doaj.org/article/5a5abd8e146f49ffb2ee2052801b4b842020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16738-zhttps://doaj.org/toc/2041-1723Caveolae are plasma membrane invaginations playing crucial functions, like signal transduction and mechanoprotection. Here, the authors show that caveolae contribute to skin pigmentation by integrating the biochemical and mechanical response of epidermal melanocytes to extracellular cues.Lia DominguesIlse HurbainFloriane Gilles-MarsensJulia Sirés-CamposNathalie AndréMelissa DewulfMaryse RomaoChristine Viaris de LesegnoAnne-Sophie MacéCédric BlouinChristelle GuéréKatell ViéGraça RaposoChristophe LamazeCédric DelevoyeNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lia Domingues Ilse Hurbain Floriane Gilles-Marsens Julia Sirés-Campos Nathalie André Melissa Dewulf Maryse Romao Christine Viaris de Lesegno Anne-Sophie Macé Cédric Blouin Christelle Guéré Katell Vié Graça Raposo Christophe Lamaze Cédric Delevoye Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation
description	Caveolae are plasma membrane invaginations playing crucial functions, like signal transduction and mechanoprotection. Here, the authors show that caveolae contribute to skin pigmentation by integrating the biochemical and mechanical response of epidermal melanocytes to extracellular cues.
format	article
author	Lia Domingues Ilse Hurbain Floriane Gilles-Marsens Julia Sirés-Campos Nathalie André Melissa Dewulf Maryse Romao Christine Viaris de Lesegno Anne-Sophie Macé Cédric Blouin Christelle Guéré Katell Vié Graça Raposo Christophe Lamaze Cédric Delevoye
author_facet	Lia Domingues Ilse Hurbain Floriane Gilles-Marsens Julia Sirés-Campos Nathalie André Melissa Dewulf Maryse Romao Christine Viaris de Lesegno Anne-Sophie Macé Cédric Blouin Christelle Guéré Katell Vié Graça Raposo Christophe Lamaze Cédric Delevoye
author_sort	Lia Domingues
title	Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation
title_short	Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation
title_full	Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation
title_fullStr	Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation
title_full_unstemmed	Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation
title_sort	coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/5a5abd8e146f49ffb2ee2052801b4b84
work_keys_str_mv	AT liadomingues couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT ilsehurbain couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT florianegillesmarsens couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT juliasirescampos couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT nathalieandre couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT melissadewulf couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT maryseromao couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT christineviarisdelesegno couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT annesophiemace couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT cedricblouin couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT christelleguere couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT katellvie couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT gracaraposo couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT christophelamaze couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation AT cedricdelevoye couplingofmelanocytesignalingandmechanicsbycaveolaeisrequiredforhumanskinpigmentation
_version_	1718379467788779520

Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation

Ejemplares similares