Epigenetic regulation of spurious transcription initiation in Arabidopsis

Epigenetic regulation can silence transposons and maintain gene expression. Here the authors survey Arabidopsis mutants defective in epigenetic regulation and show ectopic activation of thousands of cryptic TSSs and altered expression of nearby genes demonstrating the importance of suppressing spuri...

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Bibliographic Details
Main Authors: Ngoc Tu Le, Yoshiko Harukawa, Saori Miura, Damian Boer, Akira Kawabe, Hidetoshi Saze
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/5a5fa381abb64ab7be4da437d0706ed1
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Summary:Epigenetic regulation can silence transposons and maintain gene expression. Here the authors survey Arabidopsis mutants defective in epigenetic regulation and show ectopic activation of thousands of cryptic TSSs and altered expression of nearby genes demonstrating the importance of suppressing spurious transcription.