Epigenetic regulation of spurious transcription initiation in Arabidopsis

Epigenetic regulation of spurious transcription initiation in Arabidopsis

Epigenetic regulation can silence transposons and maintain gene expression. Here the authors survey Arabidopsis mutants defective in epigenetic regulation and show ectopic activation of thousands of cryptic TSSs and altered expression of nearby genes demonstrating the importance of suppressing spuri...

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Autores principales: Ngoc Tu Le, Yoshiko Harukawa, Saori Miura, Damian Boer, Akira Kawabe, Hidetoshi Saze
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/5a5fa381abb64ab7be4da437d0706ed1
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spelling oai:doaj.org-article:5a5fa381abb64ab7be4da437d0706ed12021-12-02T16:05:51ZEpigenetic regulation of spurious transcription initiation in Arabidopsis10.1038/s41467-020-16951-w2041-1723https://doaj.org/article/5a5fa381abb64ab7be4da437d0706ed12020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16951-whttps://doaj.org/toc/2041-1723Epigenetic regulation can silence transposons and maintain gene expression. Here the authors survey Arabidopsis mutants defective in epigenetic regulation and show ectopic activation of thousands of cryptic TSSs and altered expression of nearby genes demonstrating the importance of suppressing spurious transcription.Ngoc Tu LeYoshiko HarukawaSaori MiuraDamian BoerAkira KawabeHidetoshi SazeNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ngoc Tu Le
Yoshiko Harukawa
Saori Miura
Damian Boer
Akira Kawabe
Hidetoshi Saze
Epigenetic regulation of spurious transcription initiation in Arabidopsis
description Epigenetic regulation can silence transposons and maintain gene expression. Here the authors survey Arabidopsis mutants defective in epigenetic regulation and show ectopic activation of thousands of cryptic TSSs and altered expression of nearby genes demonstrating the importance of suppressing spurious transcription.
format article
author Ngoc Tu Le
Yoshiko Harukawa
Saori Miura
Damian Boer
Akira Kawabe
Hidetoshi Saze
author_facet Ngoc Tu Le
Yoshiko Harukawa
Saori Miura
Damian Boer
Akira Kawabe
Hidetoshi Saze
author_sort Ngoc Tu Le
title Epigenetic regulation of spurious transcription initiation in Arabidopsis
title_short Epigenetic regulation of spurious transcription initiation in Arabidopsis
title_full Epigenetic regulation of spurious transcription initiation in Arabidopsis
title_fullStr Epigenetic regulation of spurious transcription initiation in Arabidopsis
title_full_unstemmed Epigenetic regulation of spurious transcription initiation in Arabidopsis
title_sort epigenetic regulation of spurious transcription initiation in arabidopsis
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/5a5fa381abb64ab7be4da437d0706ed1
work_keys_str_mv AT ngoctule epigeneticregulationofspurioustranscriptioninitiationinarabidopsis
AT yoshikoharukawa epigeneticregulationofspurioustranscriptioninitiationinarabidopsis
AT saorimiura epigeneticregulationofspurioustranscriptioninitiationinarabidopsis
AT damianboer epigeneticregulationofspurioustranscriptioninitiationinarabidopsis
AT akirakawabe epigeneticregulationofspurioustranscriptioninitiationinarabidopsis
AT hidetoshisaze epigeneticregulationofspurioustranscriptioninitiationinarabidopsis
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