Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans

The transcription factor Hsf1 and the molecular chaperone Hsp90 modulate the heat shock response in the pathogen Candida albicans. Here, Leach et al. reveal a complex interplay between the two factors that regulates the expression of genes involved in the heat shock response and virulence.

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Autores principales:	Michelle D. Leach, Rhys A. Farrer, Kaeling Tan, Zhengqiang Miao, Louise A. Walker, Christina A. Cuomo, Robert T. Wheeler, Alistair J. P. Brown, Koon Ho Wong, Leah E. Cowen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5a61a55cffcb49418d894c6ff91cee45
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spelling	oai:doaj.org-article:5a61a55cffcb49418d894c6ff91cee452021-12-02T15:33:48ZHsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans10.1038/ncomms117042041-1723https://doaj.org/article/5a61a55cffcb49418d894c6ff91cee452016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11704https://doaj.org/toc/2041-1723The transcription factor Hsf1 and the molecular chaperone Hsp90 modulate the heat shock response in the pathogen Candida albicans. Here, Leach et al. reveal a complex interplay between the two factors that regulates the expression of genes involved in the heat shock response and virulence.Michelle D. LeachRhys A. FarrerKaeling TanZhengqiang MiaoLouise A. WalkerChristina A. CuomoRobert T. WheelerAlistair J. P. BrownKoon Ho WongLeah E. CowenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Michelle D. Leach Rhys A. Farrer Kaeling Tan Zhengqiang Miao Louise A. Walker Christina A. Cuomo Robert T. Wheeler Alistair J. P. Brown Koon Ho Wong Leah E. Cowen Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans
description	The transcription factor Hsf1 and the molecular chaperone Hsp90 modulate the heat shock response in the pathogen Candida albicans. Here, Leach et al. reveal a complex interplay between the two factors that regulates the expression of genes involved in the heat shock response and virulence.
format	article
author	Michelle D. Leach Rhys A. Farrer Kaeling Tan Zhengqiang Miao Louise A. Walker Christina A. Cuomo Robert T. Wheeler Alistair J. P. Brown Koon Ho Wong Leah E. Cowen
author_facet	Michelle D. Leach Rhys A. Farrer Kaeling Tan Zhengqiang Miao Louise A. Walker Christina A. Cuomo Robert T. Wheeler Alistair J. P. Brown Koon Ho Wong Leah E. Cowen
author_sort	Michelle D. Leach
title	Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans
title_short	Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans
title_full	Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans
title_fullStr	Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans
title_full_unstemmed	Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans
title_sort	hsf1 and hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in candida albicans
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/5a61a55cffcb49418d894c6ff91cee45
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Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans

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