Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection

Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection

Abstract Ductal carcinoma in situ (DCIS) is a risk factor for the subsequent development of invasive breast cancer. High-risk features include age <45 years, size >5 cm, high-grade, palpable mass, hormone receptor negativity, and HER2 positivity. We have previously shown that immune infiltrate...

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Autores principales: Alexa C. Glencer, Jasmine M. Wong, Nola M. Hylton, Gregor Krings, Emma McCune, Harriet T. Rothschild, Tristan A. Loveday, Michael D. Alvarado, Laura J. Esserman, Michael J. Campbell
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/5a661047542045b0add0bdcad86a3bf3
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