Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation

The molecular mechanisms underlying synapse formation in the olfactory bulb are not fully understood. Here the authors demonstrate that semaphorin 7A on olfactory sensory neurons, and its receptor plexin C1 expressed on mitral and tufted cells, is required for correct synapse formation.

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Autores principales:	Nobuko Inoue, Hirofumi Nishizumi, Hiromi Naritsuka, Hiroshi Kiyonari, Hitoshi Sakano
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5a6ab01c52cd49bdb30a178dccb08ebe
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spelling	oai:doaj.org-article:5a6ab01c52cd49bdb30a178dccb08ebe2021-12-02T17:31:31ZSema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation10.1038/s41467-018-04239-z2041-1723https://doaj.org/article/5a6ab01c52cd49bdb30a178dccb08ebe2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04239-zhttps://doaj.org/toc/2041-1723The molecular mechanisms underlying synapse formation in the olfactory bulb are not fully understood. Here the authors demonstrate that semaphorin 7A on olfactory sensory neurons, and its receptor plexin C1 expressed on mitral and tufted cells, is required for correct synapse formation.Nobuko InoueHirofumi NishizumiHiromi NaritsukaHiroshi KiyonariHitoshi SakanoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nobuko Inoue Hirofumi Nishizumi Hiromi Naritsuka Hiroshi Kiyonari Hitoshi Sakano Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation
description	The molecular mechanisms underlying synapse formation in the olfactory bulb are not fully understood. Here the authors demonstrate that semaphorin 7A on olfactory sensory neurons, and its receptor plexin C1 expressed on mitral and tufted cells, is required for correct synapse formation.
format	article
author	Nobuko Inoue Hirofumi Nishizumi Hiromi Naritsuka Hiroshi Kiyonari Hitoshi Sakano
author_facet	Nobuko Inoue Hirofumi Nishizumi Hiromi Naritsuka Hiroshi Kiyonari Hitoshi Sakano
author_sort	Nobuko Inoue
title	Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation
title_short	Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation
title_full	Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation
title_fullStr	Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation
title_full_unstemmed	Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation
title_sort	sema7a/plxncl signaling triggers activity-dependent olfactory synapse formation
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/5a6ab01c52cd49bdb30a178dccb08ebe
work_keys_str_mv	AT nobukoinoue sema7aplxnclsignalingtriggersactivitydependentolfactorysynapseformation AT hirofuminishizumi sema7aplxnclsignalingtriggersactivitydependentolfactorysynapseformation AT hirominaritsuka sema7aplxnclsignalingtriggersactivitydependentolfactorysynapseformation AT hiroshikiyonari sema7aplxnclsignalingtriggersactivitydependentolfactorysynapseformation AT hitoshisakano sema7aplxnclsignalingtriggersactivitydependentolfactorysynapseformation
_version_	1718380554043260928

Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation

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