Multi-resolution localization of causal variants across the genome
GWAS analysis currently relies mostly on linear mixed models, which do not account for linkage disequilibrium (LD) between tested variants. Here, Sesia et al. propose KnockoffZoom, a non-parametric statistical method for the simultaneous discovery and fine-mapping of causal variants, assuming only t...
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Autores principales: | Matteo Sesia, Eugene Katsevich, Stephen Bates, Emmanuel Candès, Chiara Sabatti |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/5a6f10c7c51540a6bf620c7a5cb1956c |
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