Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria
RNA synthesis by bacterial RNA polymerase is interrupted by pauses but their role in RNA synthesis is poorly understood. Here the authors use single-molecule FRET and biochemical analysis to show that pausing regulates branching between the abortive and productive outcomes of initial transcription.
Saved in:
Main Authors: | , , , , , , , , , , |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
|
Subjects: | |
Online Access: | https://doaj.org/article/5a7bdeadb61d4f6d961109f5e5564849 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!