Large-scale computational discovery and analysis of virus-derived microbial nanocompartments

Encapsulins are microbial protein compartments that sequester specific enzymes and are formed by self-assembly of a viral-like capsid protein. Here, Andreas and Giessen carry out a large-scale computational analysis of prokaryotic genomes to present a curated set of over 6,000 encapsulin-like system...

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Autores principales: Michael P. Andreas, Tobias W. Giessen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5a85bd094a5c416bac26763a462f15a0
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Sumario:Encapsulins are microbial protein compartments that sequester specific enzymes and are formed by self-assembly of a viral-like capsid protein. Here, Andreas and Giessen carry out a large-scale computational analysis of prokaryotic genomes to present a curated set of over 6,000 encapsulin-like systems, and present hypotheses about their potential biological functions.