Genomewide Analysis of Mode of Action of the <italic toggle="yes">S</italic>-Adenosylmethionine Analogue Sinefungin in <named-content content-type="genus-species">Leishmania infantum</named-content>

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Genomewide Analysis of Mode of Action of the <italic toggle="yes">S</italic>-Adenosylmethionine Analogue Sinefungin in <named-content content-type="genus-species">Leishmania infantum</named-content>

ABSTRACT To further our understanding of one-carbon metabolism in the protozoan parasite Leishmania, we conducted genomic screens to study how the parasite responded to sinefungin (SNF) selection. SNF is a structural analogue of S-adenosylmethionine (AdoMet), a key methyl group donor to a number of...

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Autores principales:	Arijit Bhattacharya, Mansi Sharma, Charles Packianathan, Barry P. Rosen, Philippe Leprohon, Marc Ouellette
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2019
Materias:	Leishmania single-nucleotide variants copy number variation transporter methyltransferase S-adenosylmethionine Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/5a99ca2c131d4fb080e222bd46081b2d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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