A comprehensive evaluation of module detection methods for gene expression data

Modules composed of groups of genes with similar expression profiles tend to be functionally related and co-regulated. Here, Saelens et al evaluate the performance of 42 computational methods and provide practical guidelines for module detection in gene expression data.

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Detalles Bibliográficos
Autores principales: Wouter Saelens, Robrecht Cannoodt, Yvan Saeys
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/5aabf899f0a64832b9a0b43de76a8607
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Sumario:Modules composed of groups of genes with similar expression profiles tend to be functionally related and co-regulated. Here, Saelens et al evaluate the performance of 42 computational methods and provide practical guidelines for module detection in gene expression data.