A comprehensive evaluation of module detection methods for gene expression data

Modules composed of groups of genes with similar expression profiles tend to be functionally related and co-regulated. Here, Saelens et al evaluate the performance of 42 computational methods and provide practical guidelines for module detection in gene expression data.

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Autores principales: Wouter Saelens, Robrecht Cannoodt, Yvan Saeys
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/5aabf899f0a64832b9a0b43de76a8607
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spelling oai:doaj.org-article:5aabf899f0a64832b9a0b43de76a86072021-12-02T15:33:42ZA comprehensive evaluation of module detection methods for gene expression data10.1038/s41467-018-03424-42041-1723https://doaj.org/article/5aabf899f0a64832b9a0b43de76a86072018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03424-4https://doaj.org/toc/2041-1723Modules composed of groups of genes with similar expression profiles tend to be functionally related and co-regulated. Here, Saelens et al evaluate the performance of 42 computational methods and provide practical guidelines for module detection in gene expression data.Wouter SaelensRobrecht CannoodtYvan SaeysNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wouter Saelens
Robrecht Cannoodt
Yvan Saeys
A comprehensive evaluation of module detection methods for gene expression data
description Modules composed of groups of genes with similar expression profiles tend to be functionally related and co-regulated. Here, Saelens et al evaluate the performance of 42 computational methods and provide practical guidelines for module detection in gene expression data.
format article
author Wouter Saelens
Robrecht Cannoodt
Yvan Saeys
author_facet Wouter Saelens
Robrecht Cannoodt
Yvan Saeys
author_sort Wouter Saelens
title A comprehensive evaluation of module detection methods for gene expression data
title_short A comprehensive evaluation of module detection methods for gene expression data
title_full A comprehensive evaluation of module detection methods for gene expression data
title_fullStr A comprehensive evaluation of module detection methods for gene expression data
title_full_unstemmed A comprehensive evaluation of module detection methods for gene expression data
title_sort comprehensive evaluation of module detection methods for gene expression data
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/5aabf899f0a64832b9a0b43de76a8607
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AT woutersaelens comprehensiveevaluationofmoduledetectionmethodsforgeneexpressiondata
AT robrechtcannoodt comprehensiveevaluationofmoduledetectionmethodsforgeneexpressiondata
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