A comprehensive evaluation of module detection methods for gene expression data
Modules composed of groups of genes with similar expression profiles tend to be functionally related and co-regulated. Here, Saelens et al evaluate the performance of 42 computational methods and provide practical guidelines for module detection in gene expression data.
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Nature Portfolio
2018
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oai:doaj.org-article:5aabf899f0a64832b9a0b43de76a86072021-12-02T15:33:42ZA comprehensive evaluation of module detection methods for gene expression data10.1038/s41467-018-03424-42041-1723https://doaj.org/article/5aabf899f0a64832b9a0b43de76a86072018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03424-4https://doaj.org/toc/2041-1723Modules composed of groups of genes with similar expression profiles tend to be functionally related and co-regulated. Here, Saelens et al evaluate the performance of 42 computational methods and provide practical guidelines for module detection in gene expression data.Wouter SaelensRobrecht CannoodtYvan SaeysNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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DOAJ |
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Science Q |
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Science Q Wouter Saelens Robrecht Cannoodt Yvan Saeys A comprehensive evaluation of module detection methods for gene expression data |
description |
Modules composed of groups of genes with similar expression profiles tend to be functionally related and co-regulated. Here, Saelens et al evaluate the performance of 42 computational methods and provide practical guidelines for module detection in gene expression data. |
format |
article |
author |
Wouter Saelens Robrecht Cannoodt Yvan Saeys |
author_facet |
Wouter Saelens Robrecht Cannoodt Yvan Saeys |
author_sort |
Wouter Saelens |
title |
A comprehensive evaluation of module detection methods for gene expression data |
title_short |
A comprehensive evaluation of module detection methods for gene expression data |
title_full |
A comprehensive evaluation of module detection methods for gene expression data |
title_fullStr |
A comprehensive evaluation of module detection methods for gene expression data |
title_full_unstemmed |
A comprehensive evaluation of module detection methods for gene expression data |
title_sort |
comprehensive evaluation of module detection methods for gene expression data |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/5aabf899f0a64832b9a0b43de76a8607 |
work_keys_str_mv |
AT woutersaelens acomprehensiveevaluationofmoduledetectionmethodsforgeneexpressiondata AT robrechtcannoodt acomprehensiveevaluationofmoduledetectionmethodsforgeneexpressiondata AT yvansaeys acomprehensiveevaluationofmoduledetectionmethodsforgeneexpressiondata AT woutersaelens comprehensiveevaluationofmoduledetectionmethodsforgeneexpressiondata AT robrechtcannoodt comprehensiveevaluationofmoduledetectionmethodsforgeneexpressiondata AT yvansaeys comprehensiveevaluationofmoduledetectionmethodsforgeneexpressiondata |
_version_ |
1718387025665589248 |