Inclusion of Population-specific Reference Panel from India to the 1000 Genomes Phase 3 Panel Improves Imputation Accuracy

Abstract Imputation is a computational method based on the principle of haplotype sharing allowing enrichment of genome-wide association study datasets. It depends on the haplotype structure of the population and density of the genotype data. The 1000 Genomes Project led to the generation of imputat...

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Autores principales: Meraj Ahmad, Anubhav Sinha, Sreya Ghosh, Vikrant Kumar, Sonia Davila, Chittaranjan S. Yajnik, Giriraj R. Chandak
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/5aaeda6a90ea4c0fa5f3e7dade8f0cee
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