Inclusion of Population-specific Reference Panel from India to the 1000 Genomes Phase 3 Panel Improves Imputation Accuracy
Abstract Imputation is a computational method based on the principle of haplotype sharing allowing enrichment of genome-wide association study datasets. It depends on the haplotype structure of the population and density of the genotype data. The 1000 Genomes Project led to the generation of imputat...
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Auteurs principaux: | Meraj Ahmad, Anubhav Sinha, Sreya Ghosh, Vikrant Kumar, Sonia Davila, Chittaranjan S. Yajnik, Giriraj R. Chandak |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/5aaeda6a90ea4c0fa5f3e7dade8f0cee |
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