Differentiation between chalazion and sebaceous carcinoma by noninvasive meibography

Yuji Nemoto,1 Reiko Arita,2,3 Atsushi Mizota,1 Yuko Sasajima4 1Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, 2Itoh Clinic, Saitama, 3Department of Ophthalmology, The University of Tokyo, Tokyo, 4Department of Pathology, Teikyo University School of Medicine, Tokyo, Japan...

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Autores principales:	Nemoto Y, Arita R, Mizota A, Sasajima Y
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/5ab524f760b14f2cb198c04b7be7e030
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spelling	oai:doaj.org-article:5ab524f760b14f2cb198c04b7be7e0302021-12-02T02:03:08ZDifferentiation between chalazion and sebaceous carcinoma by noninvasive meibography1177-5483https://doaj.org/article/5ab524f760b14f2cb198c04b7be7e0302014-09-01T00:00:00Zhttp://www.dovepress.com/differentiation-between-chalazion-and-sebaceous-carcinoma-by-noninvasi-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483 Yuji Nemoto,1 Reiko Arita,2,3 Atsushi Mizota,1 Yuko Sasajima4 1Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, 2Itoh Clinic, Saitama, 3Department of Ophthalmology, The University of Tokyo, Tokyo, 4Department of Pathology, Teikyo University School of Medicine, Tokyo, Japan Background: Sebaceous carcinoma is notorious for masquerading clinically as other benign lesions such as chalazion. A tool to better differentiate between these two conditions would thus be desirable.Purpose: To examine the potential application of noninvasive meibography in the differential diagnosis of chalazion and sebaceous carcinoma of the eyelid as a retrospective cross-sectional study.Methods: Five individuals with chalazion and three patients with sebaceous carcinoma were observed. Noninvasive meibography was performed to visualize the reflectivity and shape of the lesion in each subject.Results: Noninvasive meibographic imaging revealed chalazion as a lesion of overall low reflectivity with small regions of higher reflectivity corresponding to lipid granules. On the other hand, the noninvasive meibography revealed sebaceous carcinoma as a poorly marginated lesion of high reflectivity in the eyelid.Conclusion: Noninvasive meibographic imaging may prove useful for the differential diagnosis of chalazion and sebaceous carcinoma. It may also be informative in definition of the resection area in carcinoma patients. Keywords: noninvasive meibography, sebaceous carcinoma, chalazion, eyelid Nemoto YArita RMizota ASasajima YDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2014, Iss default, Pp 1869-1875 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Nemoto Y Arita R Mizota A Sasajima Y Differentiation between chalazion and sebaceous carcinoma by noninvasive meibography
description	Yuji Nemoto,1 Reiko Arita,2,3 Atsushi Mizota,1 Yuko Sasajima4 1Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, 2Itoh Clinic, Saitama, 3Department of Ophthalmology, The University of Tokyo, Tokyo, 4Department of Pathology, Teikyo University School of Medicine, Tokyo, Japan Background: Sebaceous carcinoma is notorious for masquerading clinically as other benign lesions such as chalazion. A tool to better differentiate between these two conditions would thus be desirable.Purpose: To examine the potential application of noninvasive meibography in the differential diagnosis of chalazion and sebaceous carcinoma of the eyelid as a retrospective cross-sectional study.Methods: Five individuals with chalazion and three patients with sebaceous carcinoma were observed. Noninvasive meibography was performed to visualize the reflectivity and shape of the lesion in each subject.Results: Noninvasive meibographic imaging revealed chalazion as a lesion of overall low reflectivity with small regions of higher reflectivity corresponding to lipid granules. On the other hand, the noninvasive meibography revealed sebaceous carcinoma as a poorly marginated lesion of high reflectivity in the eyelid.Conclusion: Noninvasive meibographic imaging may prove useful for the differential diagnosis of chalazion and sebaceous carcinoma. It may also be informative in definition of the resection area in carcinoma patients. Keywords: noninvasive meibography, sebaceous carcinoma, chalazion, eyelid
format	article
author	Nemoto Y Arita R Mizota A Sasajima Y
author_facet	Nemoto Y Arita R Mizota A Sasajima Y
author_sort	Nemoto Y
title	Differentiation between chalazion and sebaceous carcinoma by noninvasive meibography
title_short	Differentiation between chalazion and sebaceous carcinoma by noninvasive meibography
title_full	Differentiation between chalazion and sebaceous carcinoma by noninvasive meibography
title_fullStr	Differentiation between chalazion and sebaceous carcinoma by noninvasive meibography
title_full_unstemmed	Differentiation between chalazion and sebaceous carcinoma by noninvasive meibography
title_sort	differentiation between chalazion and sebaceous carcinoma by noninvasive meibography
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/5ab524f760b14f2cb198c04b7be7e030
work_keys_str_mv	AT nemotoy differentiationbetweenchalazionandsebaceouscarcinomabynoninvasivemeibography AT aritar differentiationbetweenchalazionandsebaceouscarcinomabynoninvasivemeibography AT mizotaa differentiationbetweenchalazionandsebaceouscarcinomabynoninvasivemeibography AT sasajimay differentiationbetweenchalazionandsebaceouscarcinomabynoninvasivemeibography
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Differentiation between chalazion and sebaceous carcinoma by noninvasive meibography

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